Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1591

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,790,609	+		Rv1589	0.31	-0.4
1,790,610	-		Rv1589	0.31	-0.3
1,790,827	+		Rv1589	0.52	-0.2
1,790,827	+		Rv1589	0.52	-0.4
1,791,084	-		Rv1589	0.76	-0.2
1,791,084	-		Rv1589	0.76	+1.8
1,791,241	+				+0.0
1,791,241	+				-0.9
1,791,242	-				-1.5
1,791,242	-				+0.7
1,791,242	-				-1.7
1,791,296	+				+0.7
1,791,296	+				-0.4
1,791,296	+				+0.3
1,791,296	+				-0.1
1,791,296	+				-1.0
1,791,297	-				-1.8
1,791,297	-				+0.1
1,791,297	-				-0.5
1,791,297	-				-0.9
1,791,297	-				-0.5
1,791,297	-				-0.3
1,791,297	-				-0.6
1,791,331	+				-0.2
1,791,386	-		Rv1590	0.22	-1.0
1,791,394	+		Rv1590	0.25	-0.9
1,791,414	+		Rv1590	0.33	-0.9
1,791,766	-		Rv1591	0.29	-0.8
1,791,766	-		Rv1591	0.29	-1.7
1,791,766	-		Rv1591	0.29	-0.2
1,791,806	+		Rv1591	0.35	-1.9
1,791,807	-		Rv1591	0.36	-0.7
1,792,026	+		Rv1591	0.68	-0.2
1,792,027	-		Rv1591	0.69	-0.6
1,792,027	-		Rv1591	0.69	-0.3
1,792,118	-		Rv1591	0.82	-1.1
1,792,197	-				-0.4
1,792,197	-				-0.1
1,792,234	-				-0.3
1,792,626	+		Rv1592c	0.17	+0.3
1,792,627	-		Rv1592c	0.17	+0.1
1,792,651	+		Rv1592c	0.19	+0.1
1,792,651	+		Rv1592c	0.19	+0.2
1,792,651	+		Rv1592c	0.19	-1.2
1,792,651	+		Rv1592c	0.19	-0.5
1,792,652	-		Rv1592c	0.19	-1.2
1,792,652	-		Rv1592c	0.19	+1.8
1,792,653	+		Rv1592c	0.19	-0.2
1,792,653	+		Rv1592c	0.19	-0.6
1,792,653	+		Rv1592c	0.19	+0.3
1,792,653	+		Rv1592c	0.19	+1.0
1,792,654	-		Rv1592c	0.19	-0.5
1,792,654	-		Rv1592c	0.19	-0.5
1,792,654	-		Rv1592c	0.19	-0.7
1,792,654	-		Rv1592c	0.19	-0.4
1,792,654	-		Rv1592c	0.19	-2.3
1,792,695	+		Rv1592c	0.22	+0.4
1,792,695	+		Rv1592c	0.22	-0.2
1,792,695	+		Rv1592c	0.22	-0.3
1,792,695	+		Rv1592c	0.22	-0.2
1,792,696	-		Rv1592c	0.22	-0.4
1,792,721	+		Rv1592c	0.24	+0.0
1,792,744	+		Rv1592c	0.26	-0.6
1,792,859	+		Rv1592c	0.34	+0.3
1,792,859	+		Rv1592c	0.34	-0.3
1,792,944	+		Rv1592c	0.41	+0.8
1,792,945	-		Rv1592c	0.41	-0.4
1,793,066	+		Rv1592c	0.50	-0.0
1,793,067	-		Rv1592c	0.50	-0.2
1,793,067	-		Rv1592c	0.50	+0.0
1,793,067	-		Rv1592c	0.50	-0.8
1,793,067	-		Rv1592c	0.50	+0.0
1,793,080	-		Rv1592c	0.51	+0.7
1,793,226	+		Rv1592c	0.62	-0.2
1,793,227	-		Rv1592c	0.62	-0.1