Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1489

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,677,676	+		Rv1488	0.24	-1.0
1,677,677	-		Rv1488	0.24	-1.7
1,677,710	-		Rv1488	0.27	+1.8
1,677,724	+		Rv1488	0.29	-0.2
1,677,724	+		Rv1488	0.29	-0.2
1,677,725	-		Rv1488	0.29	-0.0
1,677,725	-		Rv1488	0.29	+0.3
1,677,725	-		Rv1488	0.29	-0.5
1,677,725	-		Rv1488	0.29	-0.0
1,677,988	-		Rv1488	0.52	-1.6
1,677,988	-		Rv1488	0.52	-0.9
1,678,004	+		Rv1488	0.53	-1.2
1,678,004	+		Rv1488	0.53	-0.6
1,678,222	+		Rv1488	0.72	+1.8
1,678,222	+		Rv1488	0.72	+1.2
1,678,228	+		Rv1488	0.73	-0.8
1,678,228	+		Rv1488	0.73	-1.1
1,678,231	-		Rv1488	0.73	-0.1
1,678,275	-		Rv1488	0.77	-0.3
1,678,540	+				-0.5
1,678,541	-				+0.2
1,678,541	-				+1.3
1,678,579	+				+1.8
1,678,579	+				-0.8
1,678,587	-				-0.0
1,678,642	-		Rv1489	0.25	-0.7
1,678,642	-		Rv1489	0.25	-0.1
1,678,642	-		Rv1489	0.25	-0.1
1,678,642	-		Rv1489	0.25	-0.1
1,678,787	-		Rv1489	0.66	-3.6
1,678,837	-		Rv1489	0.80	-0.8
1,678,906	+				+0.5
1,678,906	+				-0.8
1,678,906	+				-0.6
1,678,907	-				+0.4
1,678,907	-				-0.3
1,678,930	+				-0.4
1,678,931	-				-0.2
1,679,190	+				+0.5
1,679,190	+				+0.0
1,679,217	-				-0.2
1,679,558	-		Rv1490	0.18	-0.3
1,679,622	+		Rv1490	0.23	+0.2
1,679,773	-		Rv1490	0.34	-0.8