Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1433

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,611,170	-				-1.1
1,611,507	+				-1.2
1,611,507	+				-0.8
1,611,508	-				-1.2
1,611,534	-		Rv1433	0.12	+0.0
1,611,558	+		Rv1433	0.15	-1.2
1,611,559	-		Rv1433	0.15	-1.2
1,611,625	+		Rv1433	0.23	-0.8
1,611,983	+		Rv1433	0.67	-0.2
1,611,983	+		Rv1433	0.67	-2.4
1,611,984	-		Rv1433	0.67	-1.7
1,612,109	+		Rv1433	0.83	-1.8
1,612,109	+		Rv1433	0.83	-1.8
1,612,110	-		Rv1433	0.83	-0.6
1,612,110	-		Rv1433	0.83	-0.9
1,612,173	+				-2.8
1,612,173	+				-0.8
1,612,202	+				-1.6
1,612,203	-				-0.6
1,612,203	-				-1.4
1,612,205	+				-0.6
1,612,205	+				+0.5
1,612,205	+				-1.0
1,612,206	-				+2.8
1,612,206	-				-1.8
1,612,247	+				-0.1
1,612,247	+				-0.2
1,612,248	-				+1.8
1,612,292	+		Rv1434	0.26	-0.4
1,612,729	-		Rv1435c	0.64	-1.5
1,612,729	-		Rv1435c	0.64	-0.7
1,612,870	+		Rv1435c	0.87	-0.9
1,612,876	+		Rv1435c	0.88	+0.2
1,612,876	+		Rv1435c	0.88	-0.9
1,612,877	-		Rv1435c	0.88	-0.0
1,612,879	-		Rv1435c	0.88	-2.6
1,612,879	-		Rv1435c	0.88	-0.3
1,613,243	+				-0.8