Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1368

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,540,050	+		Rv1367c	0.47	-0.7
1,540,050	+		Rv1367c	0.47	-0.2
1,540,089	+		Rv1367c	0.51	-1.6
1,540,089	+		Rv1367c	0.51	-0.1
1,540,090	-		Rv1367c	0.51	+0.2
1,540,090	-		Rv1367c	0.51	-0.1
1,540,090	-		Rv1367c	0.51	-0.2
1,540,207	-		Rv1367c	0.61	+0.1
1,540,207	-		Rv1367c	0.61	-0.2
1,540,300	-		Rv1367c	0.69	+0.3
1,540,300	-		Rv1367c	0.69	+0.4
1,540,679	+				-0.8
1,540,680	-				-1.0
1,540,680	-				-0.0
1,540,759	+				+0.6
1,540,759	+				+0.6
1,540,860	+				-0.3
1,540,860	+				-0.5
1,540,861	-				+0.2
1,540,961	+				-1.0
1,540,962	-				-0.3
1,540,962	-				+0.3
1,540,991	+				-1.5
1,540,992	-				-1.2
1,541,262	-		Rv1368	0.31	-0.4
1,541,438	-		Rv1368	0.53	+0.8
1,541,438	-		Rv1368	0.53	-0.2
1,541,467	+		Rv1368	0.57	-1.4
1,541,467	+		Rv1368	0.57	-0.8
1,541,467	+		Rv1368	0.57	+1.8
1,541,468	-		Rv1368	0.57	-0.6
1,541,468	-		Rv1368	0.57	-1.3
1,541,468	-		Rv1368	0.57	-1.0
1,541,630	+		Rv1368	0.78	-0.2
1,541,630	+		Rv1368	0.78	-1.2
1,541,631	-		Rv1368	0.78	-0.4
1,541,631	-		Rv1368	0.78	+0.3
1,541,635	-		Rv1368	0.78	+0.1
1,541,635	-		Rv1368	0.78	-0.0
1,541,635	-		Rv1368	0.78	-1.2