Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1290c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,442,729	+				-0.4
1,442,729	+				-0.1
1,442,729	+				+0.7
1,442,729	+				+0.6
1,442,729	+				+0.6
1,442,729	+				+1.8
1,442,729	+				-0.0
1,442,730	-				-0.3
1,442,730	-				-0.4
1,442,730	-				-0.3
1,442,730	-				+1.8
1,442,885	-		Rv1289	0.19	+0.1
1,442,944	+		Rv1289	0.28	-0.1
1,442,945	-		Rv1289	0.28	+0.8
1,443,052	+		Rv1289	0.45	-0.5
1,443,052	+		Rv1289	0.45	+0.4
1,443,119	-		Rv1289	0.56	+0.2
1,443,185	+		Rv1289	0.66	+0.6
1,443,251	-		Rv1289	0.76	-1.2
1,443,265	+		Rv1289	0.79	-0.3
1,443,266	-		Rv1289	0.79	+1.0
1,443,397	+				-0.7
1,443,433	-				-1.1
1,443,433	-				+0.0
1,443,566	+				-0.4
1,443,696	-		Rv1290c	0.14	+0.1
1,443,816	+		Rv1290c	0.21	-0.0
1,444,064	+		Rv1290c	0.37	-0.7
1,444,064	+		Rv1290c	0.37	+0.1
1,444,065	-		Rv1290c	0.37	+0.4
1,444,065	-		Rv1290c	0.37	-0.7
1,444,153	-		Rv1290c	0.43	+1.0
1,444,153	-		Rv1290c	0.43	+0.6
1,444,153	-		Rv1290c	0.43	-0.3
1,444,169	-		Rv1290c	0.44	-0.3
1,444,184	-		Rv1290c	0.45	-1.6
1,444,235	+		Rv1290c	0.48	-2.8
1,444,235	+		Rv1290c	0.48	-0.4
1,444,239	+		Rv1290c	0.48	-0.1
1,444,298	+		Rv1290c	0.52	-0.6
1,444,299	-		Rv1290c	0.52	-0.1
1,444,299	-		Rv1290c	0.52	+0.3
1,444,330	-		Rv1290c	0.54	+0.0
1,444,385	+		Rv1290c	0.58	-0.3
1,444,385	+		Rv1290c	0.58	-0.4
1,444,385	+		Rv1290c	0.58	+1.1
1,444,386	-		Rv1290c	0.58	-2.2
1,444,419	+		Rv1290c	0.60	+0.7
1,444,420	-		Rv1290c	0.60	+0.6
1,444,520	+		Rv1290c	0.66	+0.8
1,444,520	+		Rv1290c	0.66	+0.0
1,444,520	+		Rv1290c	0.66	-0.3
1,444,601	+		Rv1290c	0.71	-0.2
1,444,601	+		Rv1290c	0.71	+0.0
1,444,601	+		Rv1290c	0.71	+1.8
1,444,850	+		Rv1290c	0.87	-0.0
1,444,851	-		Rv1290c	0.87	+0.4
1,444,851	-		Rv1290c	0.87	+0.2
1,444,855	-		Rv1290c	0.88	+1.1
1,444,906	-				-0.3
1,444,940	+				+0.1
1,444,940	+				+1.2
1,444,940	+				+0.0
1,444,940	+				+0.2
1,444,941	-				-0.0
1,444,944	+				-0.2
1,444,945	-				+0.2
1,444,963	+				+0.7
1,445,187	-		Rv1290A	0.41	+0.4
1,445,391	+				-0.3
1,445,428	+				-0.2
1,445,429	-				+1.8
1,445,429	-				-0.4
1,445,501	-				+0.6
1,445,527	+				+0.1
1,445,780	+		Rv1291c	0.84	-1.8
1,445,922	-				-0.3
1,445,935	+				-0.6