Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1206 and Rv1207 are separated by 65 nucleotides Rv1207 and Rv1208 overlap by 4 nucleotides
Rv1206: Rv1206 - Probable fatty-acid-CoA ligase FadD6 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,349,332 to 1,351,125
Rv1206
Rv1207: Rv1207 - Dihydropteroate synthase 2 FolP2 (DHPS 2) (dihydropteroate pyrophosphorylase 2), at 1,351,191 to 1,352,147
Rv1207
Rv1208: Rv1208 - Probable glucosyl-3-phosphoglycerate synthase GpgS, at 1,352,144 to 1,353,118
Rv1208
Position (kb)
1351
1352
1353 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 1350.236 kb on - strand, within Rv1206 at 1350.461 kb on - strand, within Rv1206 at 1350.800 kb on - strand, within Rv1206 at 1350.902 kb on - strand, within Rv1206 at 1351.036 kb on + strand at 1351.036 kb on + strand at 1351.040 kb on + strand at 1351.041 kb on - strand at 1351.041 kb on - strand at 1351.063 kb on + strand at 1351.063 kb on + strand at 1351.063 kb on + strand at 1351.064 kb on - strand at 1351.072 kb on + strand at 1351.072 kb on + strand at 1351.073 kb on - strand at 1351.075 kb on + strand at 1351.084 kb on + strand at 1351.085 kb on - strand at 1351.183 kb on - strand at 1351.734 kb on + strand, within Rv1207 at 1351.734 kb on + strand, within Rv1207 at 1351.734 kb on + strand, within Rv1207 at 1351.735 kb on - strand, within Rv1207 at 1351.735 kb on - strand, within Rv1207 at 1351.740 kb on - strand, within Rv1207 at 1351.740 kb on - strand, within Rv1207 at 1351.773 kb on - strand, within Rv1207 at 1351.910 kb on + strand, within Rv1207 at 1351.910 kb on + strand, within Rv1207 at 1351.911 kb on - strand, within Rv1207 at 1353.139 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 1,350,236 - Rv1206 0.50 -0.2 1,350,461 - Rv1206 0.63 -0.4 1,350,800 - Rv1206 0.82 +0.4 1,350,902 - Rv1206 0.88 -0.3 1,351,036 + +0.7 1,351,036 + -0.0 1,351,040 + +0.5 1,351,041 - -1.1 1,351,041 - +0.4 1,351,063 + -0.1 1,351,063 + +2.9 1,351,063 + -1.4 1,351,064 - +0.4 1,351,072 + +0.5 1,351,072 + -0.2 1,351,073 - +0.8 1,351,075 + -0.0 1,351,084 + +0.1 1,351,085 - +1.0 1,351,183 - -2.1 1,351,734 + Rv1207 0.57 -1.6 1,351,734 + Rv1207 0.57 -0.9 1,351,734 + Rv1207 0.57 -1.5 1,351,735 - Rv1207 0.57 -0.8 1,351,735 - Rv1207 0.57 -0.3 1,351,740 - Rv1207 0.57 +0.3 1,351,740 - Rv1207 0.57 -1.3 1,351,773 - Rv1207 0.61 -1.3 1,351,910 + Rv1207 0.75 -1.4 1,351,910 + Rv1207 0.75 +0.3 1,351,911 - Rv1207 0.75 -0.7 1,353,139 + +1.3
Or see this region's nucleotide sequence