Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0969

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,077,848	+				+0.1
1,077,849	-				-0.3
1,077,849	-				+1.8
1,077,963	+				-0.6
1,077,963	+				-1.4
1,077,963	+				-0.6
1,077,964	-				+0.1
1,078,372	+				+1.8
1,078,533	+		Rv0968	0.48	-0.0
1,078,534	-		Rv0968	0.48	-0.6
1,078,534	-		Rv0968	0.48	-1.5
1,078,540	-		Rv0968	0.50	+0.7
1,079,030	-		Rv0969	0.12	-0.7
1,079,188	+		Rv0969	0.19	-0.7
1,079,357	+		Rv0969	0.27	+1.5
1,079,377	-		Rv0969	0.27	+0.2
1,079,385	+		Rv0969	0.28	+0.2
1,079,385	+		Rv0969	0.28	-0.2
1,079,385	+		Rv0969	0.28	-1.2
1,079,954	+		Rv0969	0.52	+0.3
1,080,563	-		Rv0969	0.79	+0.1
1,080,563	-		Rv0969	0.79	-0.4
1,080,563	-		Rv0969	0.79	-0.2
1,080,563	-		Rv0969	0.79	+1.2
1,080,569	-		Rv0969	0.79	+0.4
1,080,667	+		Rv0969	0.83	-0.1
1,080,668	-		Rv0969	0.83	-0.4
1,080,749	-		Rv0969	0.87	-1.0
1,080,749	-		Rv0969	0.87	-0.5
1,080,749	-		Rv0969	0.87	-0.5
1,080,817	+		Rv0969	0.90	-0.1
1,080,817	+		Rv0969	0.90	-0.2
1,080,818	-		Rv0969	0.90	-0.4
1,080,818	-		Rv0969	0.90	+1.5
1,080,885	+				+0.0
1,080,885	+				-0.8
1,080,886	-				-1.0
1,080,912	+				-0.0
1,080,912	+				+0.9
1,080,913	-				-1.9
1,081,022	-				-0.2
1,081,328	+		Rv0970	0.44	-0.2
1,081,335	-		Rv0970	0.45	+0.3
1,081,370	+		Rv0970	0.50	-0.5
1,081,370	+		Rv0970	0.50	-0.3
1,081,370	+		Rv0970	0.50	-0.2
1,081,371	-		Rv0970	0.50	+0.1
1,081,484	-		Rv0970	0.68	+0.2
1,081,620	+		Rv0970	0.90	-0.1
1,081,620	+		Rv0970	0.90	-0.4
1,081,620	+		Rv0970	0.90	-0.9
1,081,645	+				-0.7
1,081,755	+				-0.1