Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0678 and Rv0679c are separated by 55 nucleotides Rv0679c and Rv0680c are separated by 1 nucleotides Rv0680c and Rv0681 are separated by 304 nucleotides
Rv0678: Rv0678 - Conserved protein, at 778,990 to 779,487
Rv0678
Rv0679c: Rv0679c - Conserved threonine rich protein, at 779,543 to 780,040
Rv0679c
Rv0680c: Rv0680c - Probable conserved transmembrane protein, at 780,042 to 780,416
Rv0680c
Rv0681: Rv0681 - Probable transcriptional regulatory protein (possibly TetR-family), at 780,721 to 781,311
Rv0681
Position (kb)
780
781 Strain fitness (log2 ratio)
-1
0
1
2
3 at 779.263 kb on + strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.264 kb on - strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.422 kb on + strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.423 kb on - strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.424 kb on + strand, within Rv0678 at 779.425 kb on - strand, within Rv0678 at 779.459 kb on - strand at 779.797 kb on - strand, within Rv0679c at 779.914 kb on + strand, within Rv0679c at 780.066 kb on + strand at 780.066 kb on + strand at 780.066 kb on + strand at 780.075 kb on + strand at 780.075 kb on + strand at 780.076 kb on - strand at 780.076 kb on - strand at 780.142 kb on + strand, within Rv0680c at 780.143 kb on - strand, within Rv0680c at 780.482 kb on + strand at 780.482 kb on + strand at 780.482 kb on + strand at 780.483 kb on - strand at 780.483 kb on - strand at 780.483 kb on - strand at 780.574 kb on - strand at 780.582 kb on + strand at 780.582 kb on + strand at 780.583 kb on - strand at 780.583 kb on - strand at 780.583 kb on - strand at 780.854 kb on - strand, within Rv0681 at 780.854 kb on - strand, within Rv0681 at 780.854 kb on - strand, within Rv0681 at 780.881 kb on + strand, within Rv0681 at 780.881 kb on + strand, within Rv0681 at 780.998 kb on - strand, within Rv0681 at 780.998 kb on - strand, within Rv0681 at 781.066 kb on + strand, within Rv0681 at 781.066 kb on + strand, within Rv0681 at 781.066 kb on + strand, within Rv0681 at 781.067 kb on - strand, within Rv0681 at 781.120 kb on + strand, within Rv0681 at 781.296 kb on + strand at 781.309 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 779,263 + Rv0678 0.55 +2.4 779,264 - Rv0678 0.55 +2.3 779,264 - Rv0678 0.55 +1.6 779,264 - Rv0678 0.55 +1.8 779,422 + Rv0678 0.87 +2.9 779,422 + Rv0678 0.87 +1.8 779,423 - Rv0678 0.87 +1.8 779,423 - Rv0678 0.87 +2.1 779,423 - Rv0678 0.87 -1.6 779,423 - Rv0678 0.87 +0.2 779,424 + Rv0678 0.87 +1.6 779,424 + Rv0678 0.87 +2.1 779,424 + Rv0678 0.87 -0.8 779,424 + Rv0678 0.87 +1.8 779,425 - Rv0678 0.87 +1.7 779,459 - +1.9 779,797 - Rv0679c 0.51 +1.8 779,914 + Rv0679c 0.74 -0.8 780,066 + -1.2 780,066 + +1.2 780,066 + +0.3 780,075 + -1.1 780,075 + -0.4 780,076 - -0.2 780,076 - -0.2 780,142 + Rv0680c 0.27 -0.8 780,143 - Rv0680c 0.27 -0.7 780,482 + -0.2 780,482 + -0.1 780,482 + -0.6 780,483 - +0.5 780,483 - -0.2 780,483 - +0.3 780,574 - +0.2 780,582 + +0.1 780,582 + -0.3 780,583 - +0.3 780,583 - +0.5 780,583 - -0.1 780,854 - Rv0681 0.23 +2.0 780,854 - Rv0681 0.23 -0.0 780,854 - Rv0681 0.23 +0.0 780,881 + Rv0681 0.27 -0.2 780,881 + Rv0681 0.27 +1.6 780,998 - Rv0681 0.47 -0.1 780,998 - Rv0681 0.47 -0.4 781,066 + Rv0681 0.58 -0.5 781,066 + Rv0681 0.58 +0.9 781,066 + Rv0681 0.58 +0.8 781,067 - Rv0681 0.59 +0.6 781,120 + Rv0681 0.68 +0.9 781,296 + -0.5 781,309 + +0.3
Or see this region's nucleotide sequence