Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0492A and Rv0493c overlap by 4 nucleotides Rv0493c and Rv0494 are separated by 4 nucleotides Rv0494 and Rv0495c are separated by 0 nucleotides Rv0495c and Rv0496 are separated by 79 nucleotides
Rv0492A: Rv0492A - Hypothetical protein, at 583,375 to 583,704
Rv0492A
Rv0493c: Rv0493c - Conserved protein, at 583,701 to 584,690
Rv0493c
Rv0494: Rv0494 - Probable transcriptional regulatory protein (probably GntR-family), at 584,695 to 585,423
Rv0494
Rv0495c: Rv0495c - Conserved hypothetical protein, at 585,424 to 586,314
Rv0495c
Rv0496: Rv0496 - Conserved hypothetical protein, at 586,394 to 587,380
Rv0496
Position (kb)
584
585
586 Strain fitness (log2 ratio)
-1
0
1
2 at 583.864 kb on + strand, within Rv0493c at 583.865 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 583.876 kb on - strand, within Rv0493c at 584.055 kb on + strand, within Rv0493c at 584.073 kb on + strand, within Rv0493c at 584.091 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.155 kb on + strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.156 kb on - strand, within Rv0493c at 584.355 kb on - strand, within Rv0493c at 584.385 kb on + strand, within Rv0493c at 584.385 kb on + strand, within Rv0493c at 584.500 kb on + strand, within Rv0493c at 584.544 kb on + strand, within Rv0493c at 584.545 kb on - strand, within Rv0493c at 584.582 kb on - strand, within Rv0493c at 584.582 kb on - strand, within Rv0493c at 584.582 kb on - strand, within Rv0493c at 585.041 kb on + strand, within Rv0494 at 585.042 kb on - strand, within Rv0494 at 585.169 kb on + strand, within Rv0494 at 585.170 kb on - strand, within Rv0494 at 585.274 kb on + strand, within Rv0494 at 585.275 kb on - strand, within Rv0494 at 585.370 kb on + strand at 585.422 kb on - strand at 585.422 kb on - strand at 585.422 kb on - strand at 585.426 kb on - strand at 585.426 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 583,864 + Rv0493c 0.16 -1.4 583,865 - Rv0493c 0.17 +2.4 583,876 - Rv0493c 0.18 +0.6 583,876 - Rv0493c 0.18 -0.9 583,876 - Rv0493c 0.18 -0.5 584,055 + Rv0493c 0.36 +1.5 584,073 + Rv0493c 0.38 -0.6 584,091 + Rv0493c 0.39 +0.7 584,155 + Rv0493c 0.46 +0.3 584,155 + Rv0493c 0.46 -1.3 584,155 + Rv0493c 0.46 +0.5 584,155 + Rv0493c 0.46 +0.9 584,155 + Rv0493c 0.46 -0.4 584,156 - Rv0493c 0.46 +0.0 584,156 - Rv0493c 0.46 -0.8 584,156 - Rv0493c 0.46 -1.6 584,355 - Rv0493c 0.66 -0.3 584,385 + Rv0493c 0.69 -0.3 584,385 + Rv0493c 0.69 -1.5 584,500 + Rv0493c 0.81 -1.0 584,544 + Rv0493c 0.85 -0.8 584,545 - Rv0493c 0.85 -0.3 584,582 - Rv0493c 0.89 -0.7 584,582 - Rv0493c 0.89 -0.3 584,582 - Rv0493c 0.89 -0.2 585,041 + Rv0494 0.47 -0.9 585,042 - Rv0494 0.48 +0.2 585,169 + Rv0494 0.65 -0.3 585,170 - Rv0494 0.65 -0.2 585,274 + Rv0494 0.79 -0.8 585,275 - Rv0494 0.80 -1.4 585,370 + -0.1 585,422 - -0.1 585,422 - -0.5 585,422 - +0.2 585,426 - +0.0 585,426 - -1.3
Or see this region's nucleotide sequence