Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0358 and Rv0359 are separated by 10 nucleotides Rv0359 and Rv0360c are separated by 4 nucleotides Rv0360c and Rv0361 are separated by 82 nucleotides
Rv0358: Rv0358 - Conserved protein, at 436,860 to 437,507
Rv0358
Rv0359: Rv0359 - Probable conserved integral membrane protein, at 437,518 to 438,297
Rv0359
Rv0360c: Rv0360c - Conserved protein, at 438,302 to 438,739
Rv0360c
Rv0361: Rv0361 - Probable conserved membrane protein, at 438,822 to 439,649
Rv0361
Position (kb) 438
439 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 437.642 kb on - strand, within Rv0359 at 437.759 kb on - strand, within Rv0359 at 437.782 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.863 kb on + strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 437.864 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.018 kb on - strand, within Rv0359 at 438.048 kb on - strand, within Rv0359 at 438.048 kb on - strand, within Rv0359 at 438.211 kb on + strand, within Rv0359 at 438.212 kb on - strand, within Rv0359 at 438.285 kb on + strand at 438.285 kb on + strand at 438.366 kb on + strand, within Rv0360c at 438.367 kb on - strand, within Rv0360c at 438.367 kb on - strand, within Rv0360c at 438.423 kb on - strand, within Rv0360c at 438.525 kb on + strand, within Rv0360c at 438.525 kb on + strand, within Rv0360c at 438.532 kb on - strand, within Rv0360c at 438.778 kb on + strand at 438.778 kb on + strand at 439.423 kb on - strand, within Rv0361 at 439.423 kb on - strand, within Rv0361 at 439.432 kb on - strand, within Rv0361 at 439.696 kb on + strand at 439.696 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 437,642 - Rv0359 0.16 +0.1 437,759 - Rv0359 0.31 -0.4 437,782 + Rv0359 0.34 +0.3 437,863 + Rv0359 0.44 -0.5 437,863 + Rv0359 0.44 -0.8 437,863 + Rv0359 0.44 -0.8 437,864 - Rv0359 0.44 -0.0 437,864 - Rv0359 0.44 -0.0 437,864 - Rv0359 0.44 -1.1 437,864 - Rv0359 0.44 -0.8 437,864 - Rv0359 0.44 +0.1 438,018 - Rv0359 0.64 +0.4 438,018 - Rv0359 0.64 -0.2 438,018 - Rv0359 0.64 -0.5 438,048 - Rv0359 0.68 -0.2 438,048 - Rv0359 0.68 -0.0 438,211 + Rv0359 0.89 -1.3 438,212 - Rv0359 0.89 -0.2 438,285 + -0.1 438,285 + -0.1 438,366 + Rv0360c 0.15 -0.2 438,367 - Rv0360c 0.15 +1.6 438,367 - Rv0360c 0.15 +0.1 438,423 - Rv0360c 0.28 +1.8 438,525 + Rv0360c 0.51 -3.1 438,525 + Rv0360c 0.51 -0.4 438,532 - Rv0360c 0.53 +0.2 438,778 + -0.3 438,778 + +0.2 439,423 - Rv0361 0.73 -3.3 439,423 - Rv0361 0.73 -2.0 439,432 - Rv0361 0.74 -0.5 439,696 + -0.9 439,696 + +0.1
Or see this region's nucleotide sequence