Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0313 and Rv0314c are separated by 2 nucleotides Rv0314c and Rv0315 are separated by 60 nucleotides Rv0315 and Rv0316 are separated by 48 nucleotides Rv0316 and Rv0317c are separated by 23 nucleotides
Rv0313: Rv0313 - Conserved protein, at 382,490 to 382,876
Rv0313
Rv0314c: Rv0314c - Possible conserved membrane protein, at 382,879 to 383,541
Rv0314c
Rv0315: Rv0315 - Possible beta-1,3-glucanase precursor, at 383,602 to 384,486
Rv0315
Rv0316: Rv0316 - Possible muconolactone isomerase, at 384,535 to 385,149
Rv0316
Rv0317c: Rv0317c - Possible glycerophosphoryl diester phosphodiesterase GlpQ2 (glycerophosphodiester phosphodiesterase), at 385,173 to 385,943
Rv0317c
Position (kb) 383
384
385 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 382.712 kb on - strand, within Rv0313 at 382.751 kb on + strand, within Rv0313 at 382.751 kb on + strand, within Rv0313 at 382.752 kb on - strand, within Rv0313 at 382.874 kb on + strand at 382.875 kb on - strand at 382.875 kb on - strand at 382.875 kb on - strand at 382.940 kb on + strand at 382.940 kb on + strand at 383.372 kb on + strand, within Rv0314c at 383.372 kb on + strand, within Rv0314c at 383.372 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.376 kb on + strand, within Rv0314c at 383.377 kb on - strand, within Rv0314c at 383.377 kb on - strand, within Rv0314c at 383.405 kb on + strand, within Rv0314c at 383.406 kb on - strand, within Rv0314c at 383.412 kb on - strand, within Rv0314c at 383.412 kb on - strand, within Rv0314c at 383.548 kb on + strand at 383.548 kb on + strand at 383.549 kb on - strand at 383.549 kb on - strand at 383.552 kb on + strand at 383.552 kb on + strand at 383.553 kb on - strand at 383.553 kb on - strand at 383.593 kb on + strand at 383.607 kb on + strand at 383.607 kb on + strand at 383.608 kb on - strand at 383.608 kb on - strand at 383.608 kb on - strand at 383.897 kb on - strand, within Rv0315 at 384.133 kb on + strand, within Rv0315 at 384.134 kb on - strand, within Rv0315 at 384.265 kb on + strand, within Rv0315 at 384.265 kb on + strand, within Rv0315 at 384.266 kb on - strand, within Rv0315 at 384.266 kb on - strand, within Rv0315 at 384.302 kb on - strand, within Rv0315 at 384.302 kb on - strand, within Rv0315 at 384.376 kb on + strand, within Rv0315 at 384.377 kb on - strand, within Rv0315 at 384.377 kb on - strand, within Rv0315 at 384.484 kb on + strand at 384.512 kb on + strand at 384.573 kb on + strand at 384.653 kb on + strand, within Rv0316 at 384.654 kb on - strand, within Rv0316 at 384.879 kb on + strand, within Rv0316 at 384.879 kb on + strand, within Rv0316 at 384.880 kb on - strand, within Rv0316 at 385.174 kb on + strand at 385.175 kb on - strand at 385.359 kb on + strand, within Rv0317c at 385.421 kb on - strand, within Rv0317c at 385.421 kb on - strand, within Rv0317c at 385.421 kb on - strand, within Rv0317c at 385.484 kb on + strand, within Rv0317c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 382,712 - Rv0313 0.57 +0.9 382,751 + Rv0313 0.67 -0.4 382,751 + Rv0313 0.67 -0.3 382,752 - Rv0313 0.68 -0.5 382,874 + -0.1 382,875 - -0.6 382,875 - +0.1 382,875 - -0.7 382,940 + -2.6 382,940 + -0.4 383,372 + Rv0314c 0.74 +0.9 383,372 + Rv0314c 0.74 +0.3 383,372 + Rv0314c 0.74 +0.4 383,376 + Rv0314c 0.75 +1.9 383,376 + Rv0314c 0.75 +1.9 383,376 + Rv0314c 0.75 +0.7 383,377 - Rv0314c 0.75 -0.3 383,377 - Rv0314c 0.75 +0.3 383,405 + Rv0314c 0.79 +1.4 383,406 - Rv0314c 0.79 -0.0 383,412 - Rv0314c 0.80 -0.3 383,412 - Rv0314c 0.80 -0.5 383,548 + +0.1 383,548 + +0.7 383,549 - +1.9 383,549 - -0.4 383,552 + -0.1 383,552 + -0.5 383,553 - -0.1 383,553 - -1.5 383,593 + +2.0 383,607 + +0.3 383,607 + +0.7 383,608 - +0.0 383,608 - -0.6 383,608 - -0.0 383,897 - Rv0315 0.33 +0.3 384,133 + Rv0315 0.60 +0.5 384,134 - Rv0315 0.60 +0.1 384,265 + Rv0315 0.75 +3.2 384,265 + Rv0315 0.75 -0.4 384,266 - Rv0315 0.75 +0.3 384,266 - Rv0315 0.75 +2.5 384,302 - Rv0315 0.79 +0.3 384,302 - Rv0315 0.79 -0.2 384,376 + Rv0315 0.87 -0.5 384,377 - Rv0315 0.88 -0.4 384,377 - Rv0315 0.88 +0.1 384,484 + -0.3 384,512 + +0.6 384,573 + +1.9 384,653 + Rv0316 0.19 +0.3 384,654 - Rv0316 0.19 -1.7 384,879 + Rv0316 0.56 -0.1 384,879 + Rv0316 0.56 +0.0 384,880 - Rv0316 0.56 -0.1 385,174 + +0.3 385,175 - +1.0 385,359 + Rv0317c 0.24 +0.1 385,421 - Rv0317c 0.32 +0.3 385,421 - Rv0317c 0.32 -0.3 385,421 - Rv0317c 0.32 -0.1 385,484 + Rv0317c 0.40 -1.1
Or see this region's nucleotide sequence