Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0200 and Rv0201c overlap by 4 nucleotides Rv0201c and Rv0202c overlap by 4 nucleotides Rv0202c and Rv0203 are separated by 221 nucleotides Rv0203 and Rv0204c are separated by 51 nucleotides
Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895
Rv0200
Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395
Rv0201c
Rv0202c: Rv0202c - Probable conserved transmembrane transport protein MmpL11, at 238,392 to 241,292
Rv0202c
Rv0203: Rv0203 - Possible exported protein, at 241,514 to 241,924
Rv0203
Rv0204c: Rv0204c - Probable conserved transmembrane protein, at 241,976 to 243,214
Rv0204c
Position (kb) 238
239
240
241
242 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3 at 237.659 kb on + strand, within Rv0200 at 237.659 kb on + strand, within Rv0200 at 237.659 kb on + strand, within Rv0200 at 238.123 kb on - strand, within Rv0201c at 238.243 kb on + strand, within Rv0201c at 238.300 kb on - strand, within Rv0201c at 238.573 kb on + strand at 238.623 kb on - strand at 238.961 kb on + strand, within Rv0202c at 238.961 kb on + strand, within Rv0202c at 239.302 kb on - strand, within Rv0202c at 239.392 kb on + strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.591 kb on - strand, within Rv0202c at 239.856 kb on + strand, within Rv0202c at 239.970 kb on - strand, within Rv0202c at 240.303 kb on + strand, within Rv0202c at 240.303 kb on + strand, within Rv0202c at 240.304 kb on - strand, within Rv0202c at 240.403 kb on + strand, within Rv0202c at 240.404 kb on - strand, within Rv0202c at 240.404 kb on - strand, within Rv0202c at 240.547 kb on + strand, within Rv0202c at 240.547 kb on + strand, within Rv0202c at 240.731 kb on + strand, within Rv0202c at 240.817 kb on + strand, within Rv0202c at 240.817 kb on + strand, within Rv0202c at 240.818 kb on - strand, within Rv0202c at 240.818 kb on - strand, within Rv0202c at 240.870 kb on + strand, within Rv0202c at 240.943 kb on + strand, within Rv0202c at 241.014 kb on + strand at 241.015 kb on - strand at 241.055 kb on - strand at 241.058 kb on + strand at 241.059 kb on - strand at 241.059 kb on - strand at 241.183 kb on - strand at 241.210 kb on + strand at 241.210 kb on + strand at 241.348 kb on - strand at 241.558 kb on - strand, within Rv0203 at 241.691 kb on + strand, within Rv0203 at 241.692 kb on - strand, within Rv0203 at 241.799 kb on - strand, within Rv0203 at 241.923 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 237,659 + Rv0200 0.66 -0.8 237,659 + Rv0200 0.66 +2.8 237,659 + Rv0200 0.66 -0.2 238,123 - Rv0201c 0.46 -0.2 238,243 + Rv0201c 0.70 -1.0 238,300 - Rv0201c 0.81 -1.2 238,573 + -2.0 238,623 - -1.7 238,961 + Rv0202c 0.20 -2.5 238,961 + Rv0202c 0.20 -4.1 239,302 - Rv0202c 0.31 -2.1 239,392 + Rv0202c 0.34 -4.2 239,465 - Rv0202c 0.37 -1.5 239,465 - Rv0202c 0.37 -2.0 239,465 - Rv0202c 0.37 -2.2 239,591 - Rv0202c 0.41 -0.8 239,856 + Rv0202c 0.50 +0.3 239,970 - Rv0202c 0.54 -2.6 240,303 + Rv0202c 0.66 -2.3 240,303 + Rv0202c 0.66 -4.2 240,304 - Rv0202c 0.66 -0.8 240,403 + Rv0202c 0.69 -3.5 240,404 - Rv0202c 0.69 -3.3 240,404 - Rv0202c 0.69 -3.6 240,547 + Rv0202c 0.74 -2.3 240,547 + Rv0202c 0.74 -2.5 240,731 + Rv0202c 0.81 -3.3 240,817 + Rv0202c 0.84 -2.7 240,817 + Rv0202c 0.84 -4.0 240,818 - Rv0202c 0.84 -3.4 240,818 - Rv0202c 0.84 -1.9 240,870 + Rv0202c 0.85 -2.0 240,943 + Rv0202c 0.88 -1.2 241,014 + -3.8 241,015 - -2.6 241,055 - -3.4 241,058 + -3.4 241,059 - -1.3 241,059 - -3.6 241,183 - -3.4 241,210 + -2.3 241,210 + -1.7 241,348 - +0.6 241,558 - Rv0203 0.11 -0.4 241,691 + Rv0203 0.43 +0.2 241,692 - Rv0203 0.43 +2.3 241,799 - Rv0203 0.69 -0.8 241,923 - -0.3
Or see this region's nucleotide sequence