Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0142 and Rv0143c are separated by 66 nucleotides Rv0143c and Rv0144 are separated by 101 nucleotides
Rv0142: Rv0142 - Conserved hypothetical protein, at 167,711 to 168,637
Rv0142
Rv0143c: Rv0143c - Probable conserved transmembrane protein, at 168,704 to 170,182
Rv0143c
Rv0144: Rv0144 - Probable transcriptional regulatory protein (possibly TetR-family), at 170,284 to 171,126
Rv0144
Position (kb) 168
169
170
171 Strain fitness (log2 ratio) -2
-1
0
1
2 at 167.839 kb on + strand, within Rv0142 at 167.839 kb on + strand, within Rv0142 at 167.840 kb on - strand, within Rv0142 at 167.840 kb on - strand, within Rv0142 at 168.158 kb on + strand, within Rv0142 at 168.158 kb on + strand, within Rv0142 at 168.158 kb on + strand, within Rv0142 at 168.384 kb on + strand, within Rv0142 at 168.384 kb on + strand, within Rv0142 at 168.449 kb on + strand, within Rv0142 at 168.635 kb on + strand at 168.636 kb on - strand at 168.777 kb on + strand at 168.777 kb on + strand at 168.777 kb on + strand at 169.043 kb on + strand, within Rv0143c at 169.044 kb on - strand, within Rv0143c at 169.208 kb on + strand, within Rv0143c at 169.208 kb on + strand, within Rv0143c at 169.209 kb on - strand, within Rv0143c at 169.273 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.305 kb on + strand, within Rv0143c at 169.306 kb on - strand, within Rv0143c at 169.306 kb on - strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.311 kb on + strand, within Rv0143c at 169.312 kb on - strand, within Rv0143c at 169.355 kb on + strand, within Rv0143c at 169.355 kb on + strand, within Rv0143c at 169.380 kb on + strand, within Rv0143c at 169.380 kb on + strand, within Rv0143c at 169.395 kb on + strand, within Rv0143c at 169.483 kb on - strand, within Rv0143c at 169.568 kb on + strand, within Rv0143c at 169.971 kb on + strand, within Rv0143c at 169.972 kb on - strand, within Rv0143c at 169.972 kb on - strand, within Rv0143c at 170.033 kb on + strand, within Rv0143c at 170.244 kb on - strand at 170.432 kb on + strand, within Rv0144 at 170.432 kb on + strand, within Rv0144 at 170.432 kb on + strand, within Rv0144 at 170.450 kb on + strand, within Rv0144 at 170.450 kb on + strand, within Rv0144 at 170.451 kb on - strand, within Rv0144 at 170.451 kb on - strand, within Rv0144 at 170.454 kb on + strand, within Rv0144 at 170.454 kb on + strand, within Rv0144 at 170.480 kb on + strand, within Rv0144 at 170.480 kb on + strand, within Rv0144 at 170.481 kb on - strand, within Rv0144 at 170.481 kb on - strand, within Rv0144 at 170.559 kb on + strand, within Rv0144 at 170.560 kb on - strand, within Rv0144 at 170.560 kb on - strand, within Rv0144 at 170.665 kb on + strand, within Rv0144 at 170.665 kb on + strand, within Rv0144 at 170.666 kb on - strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 170.689 kb on + strand, within Rv0144 at 171.031 kb on + strand, within Rv0144 at 171.031 kb on + strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.032 kb on - strand, within Rv0144 at 171.033 kb on + strand, within Rv0144 at 171.052 kb on + strand at 171.052 kb on + strand at 171.052 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 167,839 + Rv0142 0.14 -0.2 167,839 + Rv0142 0.14 -0.0 167,840 - Rv0142 0.14 -0.2 167,840 - Rv0142 0.14 +0.7 168,158 + Rv0142 0.48 -0.4 168,158 + Rv0142 0.48 -0.2 168,158 + Rv0142 0.48 -0.5 168,384 + Rv0142 0.73 -0.6 168,384 + Rv0142 0.73 -0.5 168,449 + Rv0142 0.80 +0.2 168,635 + -0.3 168,636 - -0.1 168,777 + +0.1 168,777 + -0.1 168,777 + +0.3 169,043 + Rv0143c 0.23 +0.3 169,044 - Rv0143c 0.23 -0.4 169,208 + Rv0143c 0.34 -0.6 169,208 + Rv0143c 0.34 -0.4 169,209 - Rv0143c 0.34 -1.0 169,273 + Rv0143c 0.38 -0.1 169,305 + Rv0143c 0.41 +0.3 169,305 + Rv0143c 0.41 +0.1 169,305 + Rv0143c 0.41 -0.1 169,305 + Rv0143c 0.41 -0.3 169,306 - Rv0143c 0.41 +1.3 169,306 - Rv0143c 0.41 +0.5 169,311 + Rv0143c 0.41 +0.1 169,311 + Rv0143c 0.41 -0.5 169,311 + Rv0143c 0.41 +1.9 169,312 - Rv0143c 0.41 +0.4 169,355 + Rv0143c 0.44 +0.0 169,355 + Rv0143c 0.44 +1.0 169,380 + Rv0143c 0.46 +0.4 169,380 + Rv0143c 0.46 +0.1 169,395 + Rv0143c 0.47 +0.1 169,483 - Rv0143c 0.53 -0.3 169,568 + Rv0143c 0.58 -0.4 169,971 + Rv0143c 0.86 +0.9 169,972 - Rv0143c 0.86 +0.3 169,972 - Rv0143c 0.86 -0.1 170,033 + Rv0143c 0.90 +0.7 170,244 - -0.2 170,432 + Rv0144 0.18 -0.7 170,432 + Rv0144 0.18 -0.5 170,432 + Rv0144 0.18 -0.6 170,450 + Rv0144 0.20 +1.2 170,450 + Rv0144 0.20 -0.2 170,451 - Rv0144 0.20 +0.3 170,451 - Rv0144 0.20 -1.8 170,454 + Rv0144 0.20 +1.9 170,454 + Rv0144 0.20 -0.4 170,480 + Rv0144 0.23 +0.2 170,480 + Rv0144 0.23 -0.3 170,481 - Rv0144 0.23 -0.1 170,481 - Rv0144 0.23 -2.5 170,559 + Rv0144 0.33 +0.9 170,560 - Rv0144 0.33 -0.4 170,560 - Rv0144 0.33 -0.2 170,665 + Rv0144 0.45 -0.3 170,665 + Rv0144 0.45 -0.3 170,666 - Rv0144 0.45 -0.1 170,689 + Rv0144 0.48 +0.4 170,689 + Rv0144 0.48 -0.4 170,689 + Rv0144 0.48 +0.5 170,689 + Rv0144 0.48 +0.5 171,031 + Rv0144 0.89 -0.3 171,031 + Rv0144 0.89 -0.8 171,032 - Rv0144 0.89 +0.1 171,032 - Rv0144 0.89 +0.7 171,032 - Rv0144 0.89 +0.6 171,032 - Rv0144 0.89 -0.5 171,033 + Rv0144 0.89 +0.4 171,052 + +0.9 171,052 + -0.1 171,052 + +0.5
Or see this region's nucleotide sequence