Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3744

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
4,194,450	+		Rv3743c	0.53	-0.4
4,194,450	+		Rv3743c	0.53	+0.4
4,194,450	+		Rv3743c	0.53	+0.7
4,194,451	-		Rv3743c	0.53	-0.2
4,194,503	-		Rv3743c	0.56	+0.7
4,194,598	+		Rv3743c	0.61	-1.1
4,194,894	+		Rv3743c	0.76	-0.6
4,194,894	+		Rv3743c	0.76	-1.0
4,194,895	-		Rv3743c	0.76	+0.2
4,194,970	-		Rv3743c	0.80	-0.4
4,194,970	-		Rv3743c	0.80	-0.5
4,195,002	+		Rv3743c	0.81	-0.6
4,195,119	+		Rv3743c	0.87	-0.2
4,195,120	-		Rv3743c	0.87	-0.0
4,195,120	-		Rv3743c	0.87	-0.3
4,195,134	+		Rv3743c	0.88	-0.9
4,195,144	-		Rv3743c	0.88	-0.6
4,195,180	+				-0.2
4,195,181	-				-2.3
4,195,239	+				+0.2
4,195,240	-				+1.7
4,195,240	-				-0.5
4,195,317	+				+0.1
4,195,318	-				+0.3
4,195,318	-				-0.3
4,195,427	-				-1.4
4,195,427	-				-0.1
4,195,435	+				-2.2
4,195,435	+				-0.5
4,195,564	+		Rv3744	0.34	-0.0
4,195,565	-		Rv3744	0.34	+0.0
4,195,688	+		Rv3744	0.68	-0.4
4,195,688	+		Rv3744	0.68	-0.7
4,195,688	+		Rv3744	0.68	-0.4
4,195,688	+		Rv3744	0.68	-0.3
4,195,688	+		Rv3744	0.68	-0.3
4,195,689	-		Rv3744	0.69	-0.3
4,195,698	+		Rv3744	0.71	-1.2
4,195,699	-		Rv3744	0.71	-0.5
4,195,699	-		Rv3744	0.71	+1.7
4,195,707	+		Rv3744	0.74	-3.1
4,195,816	+				-0.5
4,195,855	+				+0.7
4,196,104	+				-0.6
4,196,104	+				+0.3
4,196,104	+				+0.4
4,196,104	+				+1.9
4,196,104	+				-0.1
4,196,105	-				-0.3
4,196,105	-				+0.7
4,196,105	-				-0.6
4,196,105	-				-0.8
4,196,105	-				-1.0
4,196,105	-				+0.1
4,196,112	+				-0.3
4,196,112	+				+0.1
4,196,112	+				-0.1
4,196,140	+				-0.1
4,196,140	+				+1.7
4,196,172	+				+0.5
4,196,173	-				+0.6
4,196,433	-		Rv3746c	0.78	+0.2
4,196,518	+				+0.0
4,196,518	+				+0.4
4,196,518	+				-0.3
4,196,628	+				+0.1
4,196,628	+				-0.7
4,196,629	-				+0.3
4,196,629	-				-1.5
4,196,646	-				-1.2
4,196,678	+				-1.6
4,196,678	+				+0.1
4,196,728	+				-0.5
4,196,729	-				-0.1
4,196,732	+				-1.3