Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3571 and Rv3572 are separated by 17 nucleotides Rv3572 and Rv3573c are separated by 35 nucleotides Rv3573c and Rv3574 are separated by 271 nucleotides Rv3574 and Rv3575c are separated by 5 nucleotides
Rv3571: Rv3571 - Reductase component of 3-ketosteroid-9-alpha-hydroxylase KshB, at 4,012,417 to 4,013,493
Rv3571
Rv3572: Rv3572 - Unknown protein, at 4,013,511 to 4,014,041
Rv3572
Rv3573c: Rv3573c - Probable acyl-CoA dehydrogenase FadE34, at 4,014,077 to 4,016,212
Rv3573c
Rv3574: Rv3574 - Transcriptional regulatory protein KstR (probably TetR-family), at 4,016,484 to 4,017,083
Rv3574
Rv3575c: Rv3575c - Transcriptional regulatory protein (probably LacI-family), at 4,017,089 to 4,018,168
Rv3575c
Position (kb)
4014
4015
4016
4017 Strain fitness (log2 ratio)
-1
0
1
2 at 4013.386 kb on - strand at 4013.483 kb on - strand at 4013.560 kb on + strand at 4013.788 kb on - strand, within Rv3572 at 4013.862 kb on + strand, within Rv3572 at 4013.862 kb on + strand, within Rv3572 at 4013.863 kb on - strand, within Rv3572 at 4013.863 kb on - strand, within Rv3572 at 4013.889 kb on + strand, within Rv3572 at 4013.966 kb on + strand, within Rv3572 at 4013.966 kb on + strand, within Rv3572 at 4013.966 kb on + strand, within Rv3572 at 4013.966 kb on + strand, within Rv3572 at 4014.043 kb on + strand at 4014.642 kb on + strand, within Rv3573c at 4014.643 kb on - strand, within Rv3573c at 4014.643 kb on - strand, within Rv3573c at 4014.647 kb on - strand, within Rv3573c at 4014.647 kb on - strand, within Rv3573c at 4015.249 kb on - strand, within Rv3573c at 4015.301 kb on - strand, within Rv3573c at 4015.695 kb on - strand, within Rv3573c at 4016.101 kb on - strand at 4016.242 kb on + strand at 4016.243 kb on - strand at 4016.243 kb on - strand at 4016.282 kb on - strand at 4016.315 kb on + strand at 4016.316 kb on - strand at 4016.316 kb on - strand at 4016.316 kb on - strand at 4016.362 kb on + strand at 4016.362 kb on + strand at 4016.363 kb on - strand at 4016.418 kb on + strand at 4016.447 kb on + strand at 4016.492 kb on - strand at 4016.644 kb on - strand, within Rv3574 at 4016.835 kb on + strand, within Rv3574 at 4017.082 kb on - strand at 4017.179 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 4,013,386 - +1.0 4,013,483 - -1.1 4,013,560 + +1.7 4,013,788 - Rv3572 0.52 -0.7 4,013,862 + Rv3572 0.66 +0.6 4,013,862 + Rv3572 0.66 -0.8 4,013,863 - Rv3572 0.66 -0.8 4,013,863 - Rv3572 0.66 -0.6 4,013,889 + Rv3572 0.71 -0.9 4,013,966 + Rv3572 0.86 -1.0 4,013,966 + Rv3572 0.86 -1.4 4,013,966 + Rv3572 0.86 -0.9 4,013,966 + Rv3572 0.86 -0.9 4,014,043 + -0.3 4,014,642 + Rv3573c 0.26 +0.6 4,014,643 - Rv3573c 0.26 -1.0 4,014,643 - Rv3573c 0.26 -0.3 4,014,647 - Rv3573c 0.27 +0.2 4,014,647 - Rv3573c 0.27 +0.1 4,015,249 - Rv3573c 0.55 -0.2 4,015,301 - Rv3573c 0.57 -0.3 4,015,695 - Rv3573c 0.76 -0.2 4,016,101 - -0.1 4,016,242 + -1.5 4,016,243 - -0.4 4,016,243 - -0.4 4,016,282 - -0.2 4,016,315 + -0.5 4,016,316 - +0.0 4,016,316 - -0.2 4,016,316 - +1.5 4,016,362 + -0.8 4,016,362 + +1.7 4,016,363 - +0.2 4,016,418 + -1.3 4,016,447 + -0.9 4,016,492 - +0.8 4,016,644 - Rv3574 0.27 +0.1 4,016,835 + Rv3574 0.58 +2.7 4,017,082 - -0.1 4,017,179 + +0.3
Or see this region's nucleotide sequence