Experiment: 7H9 with Clofazimine 0.45 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2268c and Rv2269c are separated by 12 nucleotides Rv2269c and Rv2270 are separated by 76 nucleotides Rv2270 and Rv2271 are separated by 106 nucleotides Rv2271 and Rv2272 are separated by 105 nucleotides Rv2272 and Rv2273 overlap by 4 nucleotides
Rv2268c: Rv2268c - Probable cytochrome P450 128 Cyp128, at 2,542,807 to 2,544,276
Rv2268c
Rv2269c: Rv2269c - Hypothetical protein, at 2,544,289 to 2,544,621
Rv2269c
Rv2270: Rv2270 - Probable lipoprotein LppN, at 2,544,698 to 2,545,225
Rv2270
Rv2271: Rv2271 - Conserved hypothetical protein, at 2,545,332 to 2,545,631
Rv2271
Rv2272: Rv2272 - Probable conserved transmembrane protein, at 2,545,737 to 2,546,105
Rv2272
Rv2273: Rv2273 - Probable conserved transmembrane protein, at 2,546,102 to 2,546,431
Rv2273
Position (kb)
2544
2545
2546 Strain fitness (log2 ratio)
-1
0
1 at 2543.833 kb on - strand, within Rv2268c at 2543.873 kb on + strand, within Rv2268c at 2543.895 kb on - strand, within Rv2268c at 2544.300 kb on + strand at 2544.371 kb on - strand, within Rv2269c at 2544.371 kb on - strand, within Rv2269c at 2544.491 kb on + strand, within Rv2269c at 2544.491 kb on + strand, within Rv2269c at 2544.545 kb on + strand, within Rv2269c at 2544.678 kb on - strand at 2544.725 kb on + strand at 2544.726 kb on - strand at 2544.726 kb on - strand at 2544.992 kb on + strand, within Rv2270 at 2545.113 kb on - strand, within Rv2270 at 2545.136 kb on - strand, within Rv2270 at 2545.308 kb on + strand at 2545.455 kb on + strand, within Rv2271 at 2545.597 kb on + strand, within Rv2271 at 2545.598 kb on - strand, within Rv2271 at 2545.654 kb on + strand at 2545.655 kb on - strand at 2545.655 kb on - strand at 2545.682 kb on + strand at 2546.032 kb on - strand, within Rv2272
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL remove 2,543,833 - Rv2268c 0.70 -0.8 2,543,873 + Rv2268c 0.73 +0.4 2,543,895 - Rv2268c 0.74 +0.9 2,544,300 + +0.4 2,544,371 - Rv2269c 0.25 -0.8 2,544,371 - Rv2269c 0.25 -1.1 2,544,491 + Rv2269c 0.61 -0.3 2,544,491 + Rv2269c 0.61 -0.1 2,544,545 + Rv2269c 0.77 -0.2 2,544,678 - -0.1 2,544,725 + +0.5 2,544,726 - -0.7 2,544,726 - -0.4 2,544,992 + Rv2270 0.56 -1.7 2,545,113 - Rv2270 0.79 -1.2 2,545,136 - Rv2270 0.83 -0.3 2,545,308 + -0.0 2,545,455 + Rv2271 0.41 +0.1 2,545,597 + Rv2271 0.88 +0.0 2,545,598 - Rv2271 0.89 -0.9 2,545,654 + -0.3 2,545,655 - -0.1 2,545,655 - +0.0 2,545,682 + -1.2 2,546,032 - Rv2272 0.80 -0.7
Or see this region's nucleotide sequence