Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2053c

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
2,311,604	-		Rv2052c	0.43	-0.2
2,311,624	+		Rv2052c	0.44	-0.0
2,311,667	+		Rv2052c	0.47	-0.6
2,311,910	-		Rv2052c	0.62	+0.4
2,311,964	+		Rv2052c	0.65	-0.7
2,311,964	+		Rv2052c	0.65	+0.4
2,311,964	+		Rv2052c	0.65	+0.1
2,311,964	+		Rv2052c	0.65	-0.3
2,311,965	-		Rv2052c	0.66	-0.9
2,311,965	-		Rv2052c	0.66	-0.3
2,311,965	-		Rv2052c	0.66	+0.1
2,311,985	-		Rv2052c	0.67	+0.0
2,311,985	-		Rv2052c	0.67	+0.1
2,312,024	+		Rv2052c	0.69	-0.4
2,312,108	+		Rv2052c	0.74	-0.7
2,312,109	-		Rv2052c	0.75	+0.2
2,312,109	-		Rv2052c	0.75	-0.2
2,312,137	+		Rv2052c	0.76	-0.3
2,312,245	+		Rv2052c	0.83	-2.5
2,312,246	-		Rv2052c	0.83	+0.2
2,312,475	-				+0.0
2,312,475	-				+0.0
2,312,475	-				-0.6
2,312,524	-				-0.5
2,312,524	-				-0.3
2,312,591	+		Rv2053c	0.13	-0.2
2,312,591	+		Rv2053c	0.13	-0.3
2,312,591	+		Rv2053c	0.13	-0.0
2,312,591	+		Rv2053c	0.13	+0.0
2,312,591	+		Rv2053c	0.13	+0.8
2,312,592	-		Rv2053c	0.13	-0.4
2,312,592	-		Rv2053c	0.13	+0.4
2,312,592	-		Rv2053c	0.13	+0.5
2,312,592	-		Rv2053c	0.13	-0.4
2,312,592	-		Rv2053c	0.13	+0.1
2,312,592	-		Rv2053c	0.13	-0.0
2,312,617	+		Rv2053c	0.18	-0.4
2,313,027	+				-0.0
2,313,027	+				+1.1
2,313,028	-				-0.7
2,313,074	+				+0.2
2,313,114	+				-0.0
2,313,115	-				-0.3
2,313,124	+				+0.0
2,313,124	+				+0.4
2,313,125	-				+0.1
2,313,136	-				-0.0
2,313,250	+		Rv2054	0.18	+0.5
2,313,250	+		Rv2054	0.18	-0.0
2,313,251	-		Rv2054	0.18	-0.2
2,313,284	+		Rv2054	0.22	+0.1
2,313,284	+		Rv2054	0.22	+0.4
2,313,285	-		Rv2054	0.22	-0.2
2,313,285	-		Rv2054	0.22	+0.8
2,313,285	-		Rv2054	0.22	-0.5
2,313,285	-		Rv2054	0.22	+0.7
2,313,308	+		Rv2054	0.26	-0.6
2,313,308	+		Rv2054	0.26	-0.9
2,313,308	+		Rv2054	0.26	-0.3
2,313,309	-		Rv2054	0.26	-0.0
2,313,334	+		Rv2054	0.29	-0.8
2,313,334	+		Rv2054	0.29	-1.4
2,313,335	-		Rv2054	0.29	+0.1
2,313,335	-		Rv2054	0.29	-0.2
2,313,335	-		Rv2054	0.29	+0.2
2,313,521	+		Rv2054	0.55	-0.3
2,313,521	+		Rv2054	0.55	+0.4
2,313,522	-		Rv2054	0.56	+0.6
2,313,558	+		Rv2054	0.61	+0.8
2,313,631	-		Rv2054	0.71	-0.1
2,313,634	+		Rv2054	0.71	+1.3
2,313,634	+		Rv2054	0.71	+0.0
2,313,635	-		Rv2054	0.71	-0.5
2,313,635	-		Rv2054	0.71	-0.2
2,313,635	-		Rv2054	0.71	+0.9
2,313,635	-		Rv2054	0.71	+0.2
2,313,750	-		Rv2054	0.88	-0.4
2,313,836	+				-0.3
2,313,836	+				-0.8
2,313,836	+				+0.1
2,313,837	-				+2.3
2,313,837	-				-0.4
2,313,840	+				-0.1
2,313,840	+				-0.1
2,313,841	-				-0.1
2,313,841	-				-1.0
2,313,841	-				+0.8
2,313,953	-				-0.3
2,313,953	-				-0.1
2,313,953	-				-0.4
2,313,953	-				-0.4