Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2046

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
2,290,319	+		Rv2045c	0.41	-0.2
2,290,556	-		Rv2045c	0.57	+0.4
2,290,793	+		Rv2045c	0.72	+0.1
2,290,793	+		Rv2045c	0.72	+0.4
2,290,829	+		Rv2045c	0.74	-0.3
2,290,830	-		Rv2045c	0.75	-0.4
2,290,886	-		Rv2045c	0.78	+0.0
2,291,190	+				-0.1
2,291,191	-				-0.0
2,291,340	-		Rv2046	0.11	-1.0
2,291,557	-		Rv2046	0.44	+0.5
2,291,726	-		Rv2046	0.70	-0.1
2,291,818	+		Rv2046	0.84	+1.7
2,291,957	+				-0.3
2,291,957	+				+0.5
2,291,957	+				-0.0
2,291,958	-				+1.7
2,291,958	-				-0.2
2,292,082	-				-0.3
2,292,082	-				-3.2
2,292,183	-				-4.0
2,292,319	+		Rv2047c	0.14	-2.4
2,292,743	+		Rv2047c	0.30	-4.8
2,292,841	+		Rv2047c	0.34	-1.5
2,292,842	-		Rv2047c	0.34	-3.0