Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1661

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1660 and Rv1661 are separated by 82 nucleotidesRv1661 and Rv1662 are separated by 19 nucleotides Rv1660: Rv1660 - Chalcone synthase Pks10, at 1,874,160 to 1,875,221 Rv1660 Rv1661: Rv1661 - Probable polyketide synthase Pks7, at 1,875,304 to 1,881,684 Rv1661 Rv1662: Rv1662 - Probable polyketide synthase Pks8, at 1,881,704 to 1,886,512 Rv1662 Position (kb) 1875 1876 1877 1878 1879 1880 1881 1882Strain fitness (log2 ratio) -2 -1 0 1at 1874.334 kb on + strand, within Rv1660at 1874.335 kb on - strand, within Rv1660at 1874.611 kb on - strand, within Rv1660at 1874.674 kb on - strand, within Rv1660at 1874.820 kb on + strand, within Rv1660at 1874.821 kb on - strand, within Rv1660at 1874.913 kb on + strand, within Rv1660at 1874.914 kb on - strand, within Rv1660at 1874.914 kb on - strand, within Rv1660at 1875.240 kb on + strandat 1875.581 kb on - strandat 1875.874 kb on + strandat 1875.875 kb on - strandat 1875.875 kb on - strandat 1875.875 kb on - strandat 1876.082 kb on - strand, within Rv1661at 1876.293 kb on - strand, within Rv1661at 1877.043 kb on - strand, within Rv1661at 1877.043 kb on - strand, within Rv1661at 1877.288 kb on - strand, within Rv1661at 1878.017 kb on - strand, within Rv1661at 1879.343 kb on + strand, within Rv1661at 1879.345 kb on + strand, within Rv1661at 1879.346 kb on - strand, within Rv1661at 1879.556 kb on - strand, within Rv1661at 1880.070 kb on - strand, within Rv1661at 1880.092 kb on - strand, within Rv1661at 1880.628 kb on + strand, within Rv1661at 1880.993 kb on + strand, within Rv1661at 1882.045 kb on + strand

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.45 ug/mL
remove
1,874,334 + Rv1660 0.16 -0.4
1,874,335 - Rv1660 0.16 +0.0
1,874,611 - Rv1660 0.42 +0.3
1,874,674 - Rv1660 0.48 -0.2
1,874,820 + Rv1660 0.62 +0.1
1,874,821 - Rv1660 0.62 -1.2
1,874,913 + Rv1660 0.71 +0.2
1,874,914 - Rv1660 0.71 +0.2
1,874,914 - Rv1660 0.71 -0.2
1,875,240 + +0.4
1,875,581 - -0.1
1,875,874 + +0.2
1,875,875 - -0.6
1,875,875 - -0.1
1,875,875 - +0.3
1,876,082 - Rv1661 0.12 -0.8
1,876,293 - Rv1661 0.15 -0.5
1,877,043 - Rv1661 0.27 -0.4
1,877,043 - Rv1661 0.27 -1.2
1,877,288 - Rv1661 0.31 +1.7
1,878,017 - Rv1661 0.43 -0.9
1,879,343 + Rv1661 0.63 -0.1
1,879,345 + Rv1661 0.63 +0.7
1,879,346 - Rv1661 0.63 +1.7
1,879,556 - Rv1661 0.67 -0.3
1,880,070 - Rv1661 0.75 -1.8
1,880,092 - Rv1661 0.75 -0.3
1,880,628 + Rv1661 0.83 +0.3
1,880,993 + Rv1661 0.89 +0.1
1,882,045 + +0.2

Or see this region's nucleotide sequence