Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1534

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,733,736	-		Rv1533	0.11	-0.3
1,733,826	+		Rv1533	0.19	-1.3
1,733,826	+		Rv1533	0.19	-1.9
1,733,826	+		Rv1533	0.19	+0.1
1,733,995	-		Rv1533	0.34	+0.3
1,734,822	+		Rv1534	0.13	+1.1
1,734,909	-		Rv1534	0.26	+0.0
1,735,048	-		Rv1534	0.46	-0.5
1,735,096	-		Rv1534	0.53	-0.1
1,735,113	-		Rv1534	0.56	-1.4
1,735,154	+		Rv1534	0.62	-0.6
1,735,244	+		Rv1534	0.75	-0.0
1,735,428	-				+0.3
1,735,486	+				+0.2
1,735,509	+				-0.6
1,735,544	+				-2.6
1,735,544	+				-0.6
1,735,545	-				+0.2
1,735,545	-				-1.1
1,735,545	-				-0.1
1,735,545	-				-0.7
1,735,545	-				+0.5
1,735,602	+				+1.4
1,735,704	+				+0.7
1,735,704	+				+1.0
1,735,704	+				-0.5
1,735,722	+				+3.0
1,735,739	+				-0.0
1,735,739	+				+1.0
1,735,739	+				+0.0
1,735,740	-				-0.8
1,735,740	-				-0.1
1,735,922	+				+0.6
1,735,922	+				+0.0
1,735,922	+				+0.7
1,735,923	-				-0.7
1,735,923	-				-0.4
1,735,923	-				-0.6
1,735,964	+				-0.3
1,735,964	+				-0.5
1,736,001	+		Rv1535	0.11	-0.2
1,736,001	+		Rv1535	0.11	+0.4
1,736,002	-		Rv1535	0.11	-0.9
1,736,002	-		Rv1535	0.11	+1.7
1,736,002	-		Rv1535	0.11	-0.0
1,736,002	-		Rv1535	0.11	+1.0
1,736,004	+		Rv1535	0.12	-0.4
1,736,004	+		Rv1535	0.12	+0.7
1,736,005	-		Rv1535	0.12	-0.2
1,736,005	-		Rv1535	0.12	-0.1
1,736,010	+		Rv1535	0.14	-0.0
1,736,011	-		Rv1535	0.15	-0.1
1,736,168	+		Rv1535	0.81	-1.1
1,736,169	-		Rv1535	0.81	+1.7
1,736,210	+				-0.0