Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1160

Experiment: 7H9 with Clofazimine 0.45 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.45 ug/mL
1,285,754	+		Rv1159	0.59	-2.3
1,285,902	+		Rv1159	0.70	-1.4
1,286,252	+				+0.1
1,286,252	+				+0.1
1,286,253	-				+0.2
1,286,253	-				-0.5
1,286,285	+				-2.4
1,286,285	+				-0.4
1,286,413	+		Rv1159A	0.45	-0.4
1,286,413	+		Rv1159A	0.45	-0.6
1,286,558	-				-0.1
1,286,568	+				-0.0
1,286,569	-				+0.2
1,286,579	+				-1.3
1,286,581	+				-1.1
1,286,582	-				-0.6
1,286,848	-		Rv1160	0.59	-0.6
1,286,941	+		Rv1160	0.81	+1.8
1,287,112	+				-0.1
1,287,464	-				-0.2
1,287,544	+				+0.8
1,287,619	+				-0.2
1,287,619	+				-1.2
1,287,667	+				-0.2
1,287,668	-				+0.8
1,287,695	-				-2.1
1,287,722	-		Rv1161	0.11	+1.2
1,287,722	-		Rv1161	0.11	+0.6
1,287,898	+		Rv1161	0.15	+0.3
1,287,899	-		Rv1161	0.15	-0.1
1,288,009	+		Rv1161	0.18	+1.2
1,288,019	-		Rv1161	0.19	-0.1