Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3435c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.072 ug/mL
3,853,200	+				+1.8
3,853,200	+				+0.0
3,853,201	-				-0.4
3,853,201	-				-0.1
3,853,454	-		Rv3434c	0.33	+0.3
3,853,454	-		Rv3434c	0.33	+1.8
3,853,454	-		Rv3434c	0.33	+0.8
3,853,454	-		Rv3434c	0.33	-0.4
3,853,454	-		Rv3434c	0.33	+0.0
3,853,487	-		Rv3434c	0.38	-0.2
3,853,573	+		Rv3434c	0.50	-0.3
3,853,573	+		Rv3434c	0.50	-0.1
3,853,573	+		Rv3434c	0.50	+0.7
3,853,574	-		Rv3434c	0.50	-0.1
3,853,847	-		Rv3434c	0.89	-0.3
3,853,940	+				+0.3
3,853,941	-				-0.1
3,853,941	-				-0.6
3,853,941	-				-0.8
3,853,991	+				-0.2
3,853,991	+				+0.0
3,853,991	+				+0.8
3,853,991	+				+2.3
3,853,992	-				+0.2
3,853,992	-				-0.2
3,853,992	-				-0.6
3,853,992	-				+0.8
3,854,032	+		Rv3435c	0.11	+0.0
3,854,120	+		Rv3435c	0.21	+1.2
3,854,121	-		Rv3435c	0.21	+0.2
3,854,505	+		Rv3435c	0.66	-0.2
3,854,720	+				+0.0
3,854,741	+				+0.2
3,854,911	-				-0.9
3,854,997	+				+0.1
3,855,017	-				+1.8