Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3308

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.072 ug/mL
3,693,998	+				-0.1
3,694,040	+				+0.2
3,694,268	+		Rv3307	0.27	+0.7
3,694,349	-		Rv3307	0.37	-0.4
3,694,396	-		Rv3307	0.42	-0.4
3,694,396	-		Rv3307	0.42	+0.9
3,694,396	-		Rv3307	0.42	-1.5
3,694,532	-		Rv3307	0.59	+0.0
3,694,615	+		Rv3307	0.70	-0.6
3,694,615	+		Rv3307	0.70	-0.2
3,694,730	+		Rv3307	0.84	-0.4
3,694,858	+				+0.8
3,695,300	-		Rv3308	0.27	+1.3
3,695,309	-		Rv3308	0.28	-0.5
3,695,452	-		Rv3308	0.37	+0.2
3,695,452	-		Rv3308	0.37	-0.8
3,695,452	-		Rv3308	0.37	-0.9
3,695,578	-		Rv3308	0.44	+0.4
3,696,142	+		Rv3308	0.80	-0.3
3,696,364	+				-0.0
3,696,523	-				+0.2
3,696,523	-				+0.3
3,696,726	-		Rv3309c	0.41	-2.0
3,696,972	+		Rv3309c	0.80	+0.2
3,696,972	+		Rv3309c	0.80	-1.1
3,696,972	+		Rv3309c	0.80	+0.5
3,696,973	-		Rv3309c	0.81	+0.6
3,697,107	-				+0.1
3,697,107	-				-0.3
3,697,107	-				-0.6
3,697,109	-				-0.4
3,697,110	+				-0.7
3,697,111	-				-0.1
3,697,111	-				-1.0
3,697,111	-				+0.4
3,697,187	-				-0.7
3,697,187	-				-0.2
3,697,188	+				-1.3
3,697,189	-				-1.2
3,697,189	-				+0.2
3,697,241	+				+0.1