Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3224 and Rv3224A overlap by 65 nucleotides Rv3224A and Rv3224B overlap by 23 nucleotides Rv3224B and Rv3225c overlap by 4 nucleotides Rv3225c and Rv3226c are separated by 123 nucleotides Rv3226c and Rv3227 are separated by 54 nucleotides
Rv3224: Rv3224 - Possible iron-regulated short-chain dehydrogenase/reductase, at 3,599,851 to 3,600,699
Rv3224
Rv3224A: Rv3224A - Conserved hypothetical protein, at 3,600,635 to 3,600,823
Rv3224A
Rv3224B: Rv3224B - Conserved hypothetical protein, at 3,600,801 to 3,601,019
Rv3224B
Rv3225c: Rv3225c - GCN5-related N-acetyltransferase, phosphorylase, at 3,601,016 to 3,602,440
Rv3225c
Rv3226c: Rv3226c - Conserved hypothetical protein, at 3,602,564 to 3,603,322
Rv3226c
Rv3227: Rv3227 - 3-phosphoshikimate 1-carboxyvinyltransferase AroA (5-enolpyruvylshikimate-3-phosphate synthase) (EPSP synthase) (EPSPS), at 3,603,377 to 3,604,729
Rv3227
Position (kb)
3601
3602
3603 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 3600.123 kb on + strand, within Rv3224 at 3600.124 kb on - strand, within Rv3224 at 3600.124 kb on - strand, within Rv3224 at 3600.124 kb on - strand, within Rv3224 at 3600.155 kb on + strand, within Rv3224 at 3600.155 kb on + strand, within Rv3224 at 3600.156 kb on - strand, within Rv3224 at 3600.223 kb on + strand, within Rv3224 at 3600.223 kb on + strand, within Rv3224 at 3600.224 kb on - strand, within Rv3224 at 3600.224 kb on - strand, within Rv3224 at 3600.224 kb on - strand, within Rv3224 at 3600.224 kb on - strand, within Rv3224 at 3600.230 kb on + strand, within Rv3224 at 3600.231 kb on - strand, within Rv3224 at 3600.252 kb on + strand, within Rv3224 at 3600.252 kb on + strand, within Rv3224 at 3600.253 kb on - strand, within Rv3224 at 3600.253 kb on - strand, within Rv3224 at 3600.334 kb on + strand, within Rv3224 at 3600.334 kb on + strand, within Rv3224 at 3600.335 kb on - strand, within Rv3224 at 3600.335 kb on - strand, within Rv3224 at 3600.335 kb on - strand, within Rv3224 at 3600.335 kb on - strand, within Rv3224 at 3600.349 kb on + strand, within Rv3224 at 3600.349 kb on + strand, within Rv3224 at 3600.349 kb on + strand, within Rv3224 at 3600.507 kb on - strand, within Rv3224 at 3600.507 kb on - strand, within Rv3224 at 3600.508 kb on + strand, within Rv3224 at 3600.508 kb on + strand, within Rv3224 at 3600.508 kb on + strand, within Rv3224 at 3600.509 kb on - strand, within Rv3224 at 3600.523 kb on + strand, within Rv3224 at 3600.523 kb on + strand, within Rv3224 at 3600.523 kb on + strand, within Rv3224 at 3600.524 kb on - strand, within Rv3224 at 3600.554 kb on - strand, within Rv3224 at 3600.619 kb on + strand at 3600.822 kb on - strand at 3601.030 kb on + strand at 3601.111 kb on - strand at 3601.114 kb on - strand at 3601.379 kb on + strand, within Rv3225c at 3601.451 kb on + strand, within Rv3225c at 3601.685 kb on + strand, within Rv3225c at 3601.710 kb on + strand, within Rv3225c at 3601.789 kb on - strand, within Rv3225c at 3601.832 kb on + strand, within Rv3225c at 3601.832 kb on + strand, within Rv3225c at 3601.922 kb on + strand, within Rv3225c at 3601.936 kb on - strand, within Rv3225c at 3602.074 kb on - strand, within Rv3225c at 3602.074 kb on - strand, within Rv3225c at 3602.204 kb on + strand, within Rv3225c at 3602.205 kb on - strand, within Rv3225c at 3602.283 kb on + strand, within Rv3225c at 3602.284 kb on - strand, within Rv3225c at 3602.315 kb on - strand at 3602.334 kb on - strand at 3602.847 kb on + strand, within Rv3226c at 3602.847 kb on + strand, within Rv3226c at 3602.848 kb on - strand, within Rv3226c at 3602.848 kb on - strand, within Rv3226c at 3603.043 kb on + strand, within Rv3226c at 3603.223 kb on - strand, within Rv3226c at 3603.223 kb on - strand, within Rv3226c at 3603.330 kb on - strand at 3603.330 kb on - strand at 3603.330 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 3,600,123 + Rv3224 0.32 -1.1 3,600,124 - Rv3224 0.32 +0.6 3,600,124 - Rv3224 0.32 -0.6 3,600,124 - Rv3224 0.32 -1.8 3,600,155 + Rv3224 0.36 -0.9 3,600,155 + Rv3224 0.36 -0.6 3,600,156 - Rv3224 0.36 +0.0 3,600,223 + Rv3224 0.44 -0.2 3,600,223 + Rv3224 0.44 +1.1 3,600,224 - Rv3224 0.44 -0.4 3,600,224 - Rv3224 0.44 -0.7 3,600,224 - Rv3224 0.44 +0.4 3,600,224 - Rv3224 0.44 +0.4 3,600,230 + Rv3224 0.45 +1.5 3,600,231 - Rv3224 0.45 +0.1 3,600,252 + Rv3224 0.47 +0.4 3,600,252 + Rv3224 0.47 +0.5 3,600,253 - Rv3224 0.47 -0.4 3,600,253 - Rv3224 0.47 -1.2 3,600,334 + Rv3224 0.57 -0.3 3,600,334 + Rv3224 0.57 -0.6 3,600,335 - Rv3224 0.57 +0.1 3,600,335 - Rv3224 0.57 +2.4 3,600,335 - Rv3224 0.57 +0.8 3,600,335 - Rv3224 0.57 +0.2 3,600,349 + Rv3224 0.59 -0.0 3,600,349 + Rv3224 0.59 +0.7 3,600,349 + Rv3224 0.59 -0.0 3,600,507 - Rv3224 0.77 -1.1 3,600,507 - Rv3224 0.77 -0.5 3,600,508 + Rv3224 0.77 +0.5 3,600,508 + Rv3224 0.77 -0.0 3,600,508 + Rv3224 0.77 -0.3 3,600,509 - Rv3224 0.78 -0.1 3,600,523 + Rv3224 0.79 -0.7 3,600,523 + Rv3224 0.79 -0.1 3,600,523 + Rv3224 0.79 +0.2 3,600,524 - Rv3224 0.79 -0.6 3,600,554 - Rv3224 0.83 -0.8 3,600,619 + -0.0 3,600,822 - -0.9 3,601,030 + -0.0 3,601,111 - -0.3 3,601,114 - -0.9 3,601,379 + Rv3225c 0.25 +1.0 3,601,451 + Rv3225c 0.31 +0.4 3,601,685 + Rv3225c 0.47 -0.4 3,601,710 + Rv3225c 0.49 -0.5 3,601,789 - Rv3225c 0.54 -0.1 3,601,832 + Rv3225c 0.57 -0.1 3,601,832 + Rv3225c 0.57 +0.3 3,601,922 + Rv3225c 0.64 -0.2 3,601,936 - Rv3225c 0.65 -0.2 3,602,074 - Rv3225c 0.74 -0.3 3,602,074 - Rv3225c 0.74 +1.1 3,602,204 + Rv3225c 0.83 -0.1 3,602,205 - Rv3225c 0.83 +1.8 3,602,283 + Rv3225c 0.89 +0.1 3,602,284 - Rv3225c 0.89 +1.3 3,602,315 - +0.1 3,602,334 - -0.3 3,602,847 + Rv3226c 0.37 +0.8 3,602,847 + Rv3226c 0.37 +0.8 3,602,848 - Rv3226c 0.37 -0.3 3,602,848 - Rv3226c 0.37 -0.6 3,603,043 + Rv3226c 0.63 -0.1 3,603,223 - Rv3226c 0.87 +0.3 3,603,223 - Rv3226c 0.87 +1.8 3,603,330 - +0.5 3,603,330 - -0.2 3,603,330 - -0.1
Or see this region's nucleotide sequence