Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1036c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1034c and Rv1035c are separated by 67 nucleotidesRv1035c and Rv1036c are separated by 33 nucleotidesRv1036c and Rv1037c are separated by 110 nucleotidesRv1037c and Rv1038c are separated by 26 nucleotidesRv1038c and Rv1039c are separated by 145 nucleotides Rv1034c: Rv1034c - Probable transposase (fragment), at 1,158,918 to 1,159,307 Rv1034c Rv1035c: Rv1035c - Probable transposase (fragment), at 1,159,375 to 1,160,061 Rv1035c Rv1036c: Rv1036c - Probable IS1560 transposase (fragment), at 1,160,095 to 1,160,433 Rv1036c Rv1037c: Rv1037c - Putative ESAT-6 like protein EsxI (ESAT-6 like protein 1), at 1,160,544 to 1,160,828 Rv1037c Rv1038c: Rv1038c - ESAT-6 like protein EsxJ (ESAT-6 like protein 2), at 1,160,855 to 1,161,151 Rv1038c Rv1039c: Rv1039c - PPE family protein PPE15, at 1,161,297 to 1,162,472 Rv1039c Position (kb) 1160 1161Strain fitness (log2 ratio) -2 -1 0 1at 1159.516 kb on + strand, within Rv1035cat 1159.902 kb on - strand, within Rv1035cat 1160.177 kb on + strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.345 kb on - strand, within Rv1036cat 1160.446 kb on - strandat 1160.446 kb on - strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.458 kb on + strandat 1160.459 kb on - strandat 1160.463 kb on - strandat 1160.463 kb on - strandat 1160.516 kb on - strandat 1160.534 kb on + strandat 1160.534 kb on + strandat 1160.534 kb on + strandat 1160.535 kb on - strandat 1160.546 kb on - strandat 1161.239 kb on + strandat 1161.254 kb on - strandat 1161.340 kb on + strandat 1161.355 kb on + strandat 1161.356 kb on - strandat 1161.356 kb on - strandat 1161.356 kb on - strandat 1161.356 kb on - strandat 1161.356 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL
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1,159,516 + Rv1035c 0.21 -0.3
1,159,902 - Rv1035c 0.77 +0.3
1,160,177 + Rv1036c 0.24 -1.1
1,160,178 - Rv1036c 0.24 -0.3
1,160,178 - Rv1036c 0.24 -0.2
1,160,178 - Rv1036c 0.24 -0.2
1,160,178 - Rv1036c 0.24 -1.3
1,160,345 - Rv1036c 0.74 -0.1
1,160,446 - -0.3
1,160,446 - +0.7
1,160,458 + -0.5
1,160,458 + -0.2
1,160,458 + -0.2
1,160,458 + -0.1
1,160,459 - -0.1
1,160,463 - -0.1
1,160,463 - -1.4
1,160,516 - +0.2
1,160,534 + -0.1
1,160,534 + -0.1
1,160,534 + -0.4
1,160,535 - +1.4
1,160,546 - -0.4
1,161,239 + -1.1
1,161,254 - -0.9
1,161,340 + +0.7
1,161,355 + -2.2
1,161,356 - -0.8
1,161,356 - +0.2
1,161,356 - +0.2
1,161,356 - -0.2
1,161,356 - -1.3

Or see this region's nucleotide sequence