Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0436c and Rv0437c overlap by 4 nucleotides Rv0437c and Rv0438c are separated by 60 nucleotides Rv0438c and Rv0439c are separated by 18 nucleotides
Rv0436c: Rv0436c - Probable CDP-diacylglycerol--serine O-phosphatidyltransferase PssA (PS synthase) (phosphatidylserine synthase), at 524,530 to 525,390
Rv0436c
Rv0437c: Rv0437c - Possible phosphatidylserine decarboxylase Psd (PS decarboxylase), at 525,387 to 526,082
Rv0437c
Rv0438c: Rv0438c - Probable molybdopterin biosynthesis protein MoeA2, at 526,143 to 527,360
Rv0438c
Rv0439c: Rv0439c - Probable dehydrogenase/reductase, at 527,379 to 528,314
Rv0439c
Position (kb) 526
527
528 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 525.347 kb on - strand at 525.359 kb on - strand at 525.359 kb on - strand at 525.470 kb on - strand, within Rv0437c at 525.506 kb on - strand, within Rv0437c at 526.093 kb on + strand at 526.093 kb on + strand at 526.093 kb on + strand at 526.094 kb on - strand at 526.145 kb on - strand at 526.297 kb on - strand, within Rv0438c at 526.558 kb on + strand, within Rv0438c at 526.559 kb on - strand, within Rv0438c at 526.594 kb on + strand, within Rv0438c at 526.595 kb on - strand, within Rv0438c at 526.763 kb on - strand, within Rv0438c at 526.779 kb on + strand, within Rv0438c at 526.780 kb on - strand, within Rv0438c at 527.201 kb on - strand, within Rv0438c at 527.201 kb on - strand, within Rv0438c at 527.201 kb on - strand, within Rv0438c at 527.297 kb on + strand at 527.388 kb on + strand at 527.515 kb on + strand, within Rv0439c at 527.515 kb on + strand, within Rv0439c at 527.518 kb on + strand, within Rv0439c at 527.518 kb on + strand, within Rv0439c at 527.518 kb on + strand, within Rv0439c at 527.519 kb on - strand, within Rv0439c at 527.627 kb on + strand, within Rv0439c at 527.731 kb on + strand, within Rv0439c at 527.731 kb on + strand, within Rv0439c at 527.785 kb on + strand, within Rv0439c at 528.171 kb on + strand, within Rv0439c at 528.171 kb on + strand, within Rv0439c at 528.172 kb on - strand, within Rv0439c at 528.172 kb on - strand, within Rv0439c at 528.172 kb on - strand, within Rv0439c at 528.288 kb on - strand at 528.288 kb on - strand at 528.288 kb on - strand at 528.288 kb on - strand at 528.325 kb on + strand at 528.325 kb on + strand at 528.326 kb on - strand at 528.326 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 525,347 - +0.7 525,359 - -1.0 525,359 - -0.3 525,470 - Rv0437c 0.12 +1.8 525,506 - Rv0437c 0.17 +0.5 526,093 + +0.4 526,093 + -1.6 526,093 + -0.2 526,094 - +0.2 526,145 - -0.2 526,297 - Rv0438c 0.13 -1.6 526,558 + Rv0438c 0.34 -0.0 526,559 - Rv0438c 0.34 -1.0 526,594 + Rv0438c 0.37 -0.4 526,595 - Rv0438c 0.37 -0.1 526,763 - Rv0438c 0.51 +3.3 526,779 + Rv0438c 0.52 -1.3 526,780 - Rv0438c 0.52 -1.6 527,201 - Rv0438c 0.87 -0.3 527,201 - Rv0438c 0.87 +0.1 527,201 - Rv0438c 0.87 -0.8 527,297 + -0.4 527,388 + -0.1 527,515 + Rv0439c 0.15 -0.6 527,515 + Rv0439c 0.15 -0.1 527,518 + Rv0439c 0.15 -0.3 527,518 + Rv0439c 0.15 -0.4 527,518 + Rv0439c 0.15 -0.1 527,519 - Rv0439c 0.15 +1.3 527,627 + Rv0439c 0.26 +0.3 527,731 + Rv0439c 0.38 +0.1 527,731 + Rv0439c 0.38 +0.3 527,785 + Rv0439c 0.43 +0.1 528,171 + Rv0439c 0.85 -1.8 528,171 + Rv0439c 0.85 -0.1 528,172 - Rv0439c 0.85 -0.2 528,172 - Rv0439c 0.85 -0.4 528,172 - Rv0439c 0.85 -0.7 528,288 - +0.0 528,288 - -0.2 528,288 - -0.5 528,288 - -0.8 528,325 + -1.2 528,325 + -0.0 528,326 - +0.0 528,326 - -0.1
Or see this region's nucleotide sequence