Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0312

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0311 and Rv0312 are separated by 154 nucleotidesRv0312 and Rv0313 are separated by 71 nucleotidesRv0313 and Rv0314c are separated by 2 nucleotides Rv0311: Rv0311 - Unknown protein, at 379,172 to 380,401 Rv0311 Rv0312: Rv0312 - Conserved hypothetical proline and threonine rich protein, at 380,556 to 382,418 Rv0312 Rv0313: Rv0313 - Conserved protein, at 382,490 to 382,876 Rv0313 Rv0314c: Rv0314c - Possible conserved membrane protein, at 382,879 to 383,541 Rv0314c Position (kb) 380 381 382 383Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 380.076 kb on + strand, within Rv0311at 380.555 kb on + strandat 380.555 kb on + strandat 380.903 kb on - strand, within Rv0312at 382.032 kb on - strand, within Rv0312at 382.459 kb on + strandat 382.459 kb on + strandat 382.463 kb on - strandat 382.463 kb on - strandat 382.712 kb on - strand, within Rv0313at 382.751 kb on + strand, within Rv0313at 382.751 kb on + strand, within Rv0313at 382.752 kb on - strand, within Rv0313at 382.874 kb on + strandat 382.875 kb on - strandat 382.875 kb on - strandat 382.875 kb on - strandat 382.940 kb on + strandat 382.940 kb on + strandat 383.372 kb on + strand, within Rv0314cat 383.372 kb on + strand, within Rv0314cat 383.372 kb on + strand, within Rv0314cat 383.376 kb on + strand, within Rv0314cat 383.376 kb on + strand, within Rv0314cat 383.376 kb on + strand, within Rv0314cat 383.377 kb on - strand, within Rv0314cat 383.377 kb on - strand, within Rv0314cat 383.405 kb on + strand, within Rv0314cat 383.406 kb on - strand, within Rv0314cat 383.412 kb on - strand, within Rv0314cat 383.412 kb on - strand, within Rv0314c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL
remove
380,076 + Rv0311 0.73 -2.1
380,555 + -0.6
380,555 + -0.6
380,903 - Rv0312 0.19 -0.3
382,032 - Rv0312 0.79 -0.0
382,459 + -0.3
382,459 + -0.5
382,463 - -0.0
382,463 - +0.4
382,712 - Rv0313 0.57 -0.2
382,751 + Rv0313 0.67 +0.6
382,751 + Rv0313 0.67 +0.4
382,752 - Rv0313 0.68 -0.6
382,874 + -0.2
382,875 - -1.2
382,875 - -0.4
382,875 - -0.7
382,940 + -1.2
382,940 + +1.0
383,372 + Rv0314c 0.74 +0.8
383,372 + Rv0314c 0.74 +0.4
383,372 + Rv0314c 0.74 +0.6
383,376 + Rv0314c 0.75 +4.1
383,376 + Rv0314c 0.75 +1.7
383,376 + Rv0314c 0.75 -0.5
383,377 - Rv0314c 0.75 +0.6
383,377 - Rv0314c 0.75 +0.8
383,405 + Rv0314c 0.79 +2.0
383,406 - Rv0314c 0.79 -0.6
383,412 - Rv0314c 0.80 +0.0
383,412 - Rv0314c 0.80 -0.3

Or see this region's nucleotide sequence