Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3687c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.072 ug/mL
4,128,355	+		Rv3685c	0.74	+0.2
4,128,356	-		Rv3685c	0.74	-0.7
4,128,553	+		Rv3685c	0.88	-0.3
4,128,661	-				-0.0
4,128,844	-		Rv3686c	0.28	-0.6
4,128,844	-		Rv3686c	0.28	-0.3
4,128,844	-		Rv3686c	0.28	-0.1
4,128,844	-		Rv3686c	0.28	-0.2
4,128,861	+		Rv3686c	0.33	+0.3
4,128,863	+		Rv3686c	0.34	-0.3
4,128,863	+		Rv3686c	0.34	-0.3
4,128,863	+		Rv3686c	0.34	-0.9
4,128,864	-		Rv3686c	0.34	-1.5
4,128,946	+		Rv3686c	0.59	-0.2
4,128,947	-		Rv3686c	0.59	-0.9
4,129,076	+				-0.1
4,129,077	-				-0.9
4,129,126	+				-0.2
4,129,127	-				+0.4
4,129,277	+				-0.9
4,129,278	-				-0.4
4,129,278	-				-0.2
4,129,278	-				-0.8
4,129,316	+				-1.1
4,129,347	+				-0.0
4,129,649	+		Rv3687c	0.88	-1.0
4,129,846	-				-0.6
4,129,871	+				-0.4
4,129,872	-				+2.0
4,129,873	+				-0.1
4,129,873	+				+0.6
4,129,873	+				-1.8
4,129,873	+				-0.8
4,129,873	+				-0.9
4,129,874	-				+2.6
4,129,874	-				-0.2
4,129,894	+				+0.2
4,129,895	-				+0.3
4,129,895	-				+0.3
4,129,896	+				+0.1
4,130,083	+		Rv3688c	0.41	-0.1
4,130,083	+		Rv3688c	0.41	-0.2
4,130,083	+		Rv3688c	0.41	-0.1
4,130,149	+		Rv3688c	0.55	-0.6
4,130,149	+		Rv3688c	0.55	-0.3
4,130,150	-		Rv3688c	0.55	-0.3
4,130,277	+		Rv3688c	0.83	-0.4
4,130,278	-		Rv3688c	0.83	-1.2
4,130,345	+				-0.6
4,130,405	+				+0.5
4,130,405	+				-0.8
4,130,405	+				+0.3
4,130,406	-				+0.1
4,130,528	+		Rv3689	0.13	-0.2
4,130,529	-		Rv3689	0.13	+0.6
4,130,561	-		Rv3689	0.15	-0.2
4,130,561	-		Rv3689	0.15	-1.0
4,130,588	+		Rv3689	0.17	-0.0
4,130,589	-		Rv3689	0.17	-0.8
4,130,606	+		Rv3689	0.18	+0.6
4,130,606	+		Rv3689	0.18	-0.7
4,130,606	+		Rv3689	0.18	-0.1
4,130,607	-		Rv3689	0.18	-0.5
4,130,625	-		Rv3689	0.20	-0.1