Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3673c and Rv3674c overlap by 1 nucleotides Rv3674c and Rv3675 are separated by 107 nucleotides Rv3675 and Rv3676 are separated by 98 nucleotides Rv3676 and Rv3677c are separated by 105 nucleotides
Rv3673c: Rv3673c - Possible membrane-anchored thioredoxin-like protein (thiol-disulfide interchange related protein), at 4,114,474 to 4,115,157
Rv3673c
Rv3674c: Rv3674c - Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)), at 4,115,157 to 4,115,894
Rv3674c
Rv3675: Rv3675 - Possible membrane protein, at 4,116,002 to 4,116,379
Rv3675
Rv3676: Rv3676 - Transcriptional regulatory protein Crp (Crp/Fnr-family), at 4,116,478 to 4,117,152
Rv3676
Rv3677c: Rv3677c - Possible hydrolase, at 4,117,258 to 4,118,052
Rv3677c
Position (kb) 4116
4117 Strain fitness (log2 ratio) -2
-1
0
1
2 at 4115.158 kb on + strand at 4115.159 kb on - strand at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.575 kb on - strand, within Rv3674c at 4115.671 kb on + strand, within Rv3674c at 4115.672 kb on - strand, within Rv3674c at 4115.751 kb on + strand, within Rv3674c at 4115.802 kb on + strand, within Rv3674c at 4115.803 kb on - strand, within Rv3674c at 4115.957 kb on + strand at 4115.958 kb on - strand at 4116.007 kb on + strand at 4116.008 kb on - strand at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.167 kb on - strand, within Rv3675 at 4116.304 kb on + strand, within Rv3675 at 4116.405 kb on + strand at 4116.447 kb on + strand at 4117.184 kb on + strand at 4117.185 kb on - strand at 4117.185 kb on - strand at 4117.275 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 4,115,158 + +0.3 4,115,159 - -0.0 4,115,575 - Rv3674c 0.57 -0.2 4,115,575 - Rv3674c 0.57 -0.5 4,115,575 - Rv3674c 0.57 -0.4 4,115,671 + Rv3674c 0.70 -0.4 4,115,672 - Rv3674c 0.70 +0.0 4,115,751 + Rv3674c 0.80 -0.4 4,115,802 + Rv3674c 0.87 -1.0 4,115,803 - Rv3674c 0.88 -0.7 4,115,957 + +2.0 4,115,958 - -2.4 4,116,007 + -0.2 4,116,008 - +0.6 4,116,167 - Rv3675 0.44 -0.9 4,116,167 - Rv3675 0.44 -0.5 4,116,167 - Rv3675 0.44 -0.0 4,116,167 - Rv3675 0.44 +0.1 4,116,304 + Rv3675 0.80 +0.0 4,116,405 + +1.2 4,116,447 + -2.4 4,117,184 + -1.4 4,117,185 - -0.0 4,117,185 - -0.0 4,117,275 - +0.3
Or see this region's nucleotide sequence