Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2578c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.072 ug/mL
2,901,575	+		Rv2577	0.41	+0.7
2,901,575	+		Rv2577	0.41	+1.6
2,901,729	-		Rv2577	0.51	+2.0
2,901,774	+		Rv2577	0.54	-0.9
2,901,774	+		Rv2577	0.54	-0.1
2,901,775	-		Rv2577	0.54	-0.5
2,901,779	+		Rv2577	0.54	-2.0
2,901,780	-		Rv2577	0.54	-0.1
2,901,861	+		Rv2577	0.59	-1.0
2,901,862	-		Rv2577	0.59	+1.4
2,901,862	-		Rv2577	0.59	-0.6
2,901,862	-		Rv2577	0.59	+0.1
2,902,027	-		Rv2577	0.70	-0.3
2,902,043	+		Rv2577	0.71	+0.7
2,902,044	-		Rv2577	0.71	+0.4
2,902,194	+		Rv2577	0.80	-0.9
2,902,301	-		Rv2577	0.87	-0.6
2,902,358	-				+0.3
2,902,412	-				-1.2
2,902,412	-				-2.0
2,902,533	+				-0.1
2,902,588	+				+0.4
2,902,589	-				-1.3
2,902,634	-		Rv2578c	0.12	+0.2
2,902,645	-		Rv2578c	0.13	+0.5
2,902,648	+		Rv2578c	0.14	+0.4
2,902,648	+		Rv2578c	0.14	-0.1
2,902,648	+		Rv2578c	0.14	+0.5
2,903,300	-		Rv2578c	0.77	+0.4
2,903,531	+				-0.4
2,903,601	+				-0.1
2,903,601	+				-0.3
2,903,601	+				-0.0
2,903,602	-				-0.4
2,903,602	-				-0.2
2,903,639	-				-1.1
2,903,678	+				-0.6
2,903,683	-				-0.5
2,903,683	-				-0.1
2,903,708	+				+0.0
2,903,708	+				+0.1
2,903,709	-				-0.9
2,903,709	-				-0.5
2,903,768	+		Rv2579	0.14	+0.4
2,903,768	+		Rv2579	0.14	-0.6
2,903,769	-		Rv2579	0.14	-0.6
2,903,769	-		Rv2579	0.14	-0.1
2,903,769	-		Rv2579	0.14	-0.5
2,903,880	-		Rv2579	0.27	-0.4
2,903,882	-		Rv2579	0.27	-0.2
2,903,882	-		Rv2579	0.27	-1.0
2,903,882	-		Rv2579	0.27	+0.6
2,903,885	+		Rv2579	0.27	+1.4
2,903,886	-		Rv2579	0.27	+1.0
2,903,886	-		Rv2579	0.27	-0.7
2,903,950	-		Rv2579	0.34	-1.3