Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2048c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Clofazimine 0.072 ug/mL
2,293,897	+		Rv2047c	0.75	-2.1
2,293,914	+		Rv2047c	0.76	-2.2
2,293,983	+		Rv2047c	0.79	-1.7
2,294,078	+		Rv2047c	0.82	-1.4
2,294,078	+		Rv2047c	0.82	-1.6
2,294,724	-				+1.0
2,294,793	+				-0.0
2,298,252	+		Rv2048c	0.30	-2.5
2,298,252	+		Rv2048c	0.30	-1.3
2,300,355	+		Rv2048c	0.47	-1.3
2,301,090	-		Rv2048c	0.53	-0.7
2,302,542	+		Rv2048c	0.64	-1.4
2,302,543	-		Rv2048c	0.64	-0.9
2,302,981	-		Rv2048c	0.68	-2.5
2,302,981	-		Rv2048c	0.68	-1.7
2,303,004	-		Rv2048c	0.68	-0.0
2,303,781	+		Rv2048c	0.74	-1.6
2,303,782	-		Rv2048c	0.74	+0.1
2,304,739	-		Rv2048c	0.82	-1.5
2,304,739	-		Rv2048c	0.82	-2.4
2,306,473	-				-1.0
2,306,709	+				-1.0
2,306,710	-				-1.6
2,306,716	+				-1.3
2,306,988	-				-0.7
2,306,990	+				-1.2
2,306,991	-				-1.1
2,306,991	-				-1.1
2,307,000	+				-1.3
2,307,001	-				+1.0
2,307,010	+				-0.8
2,307,014	-				-0.2
2,307,014	-				+0.2
2,307,117	+				-1.3
2,307,117	+				-1.8
2,307,118	-				-0.9
2,307,153	-				-0.5
2,307,254	-				-1.0
2,307,294	+				+0.7
2,307,429	+		Rv2049c	0.60	-0.5
2,307,531	+				-0.3
2,307,561	+				-0.2
2,307,656	+				+0.1
2,307,656	+				-0.3
2,307,656	+				-0.4
2,307,657	-				+0.4
2,307,657	-				-0.8
2,307,723	+				-0.7
2,307,776	+				+0.4