Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0400c

Experiment: 7H9 with Clofazimine 0.072 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0399c and Rv0400c are separated by 9 nucleotidesRv0400c and Rv0401 are separated by 35 nucleotidesRv0401 and Rv0402c are separated by 194 nucleotides Rv0399c: Rv0399c - Possible conserved lipoprotein LpqK, at 477,327 to 478,556 Rv0399c Rv0400c: Rv0400c - Acyl-CoA dehydrogenase FadE7, at 478,566 to 479,753 Rv0400c Rv0401: Rv0401 - Probable conserved transmembrane protein, at 479,789 to 480,160 Rv0401 Rv0402c: Rv0402c - Probable conserved transmembrane transport protein MmpL1, at 480,355 to 483,231 Rv0402c Position (kb) 478 479 480Strain fitness (log2 ratio) -2 -1 0 1at 477.566 kb on - strand, within Rv0399cat 477.656 kb on - strand, within Rv0399cat 478.152 kb on + strand, within Rv0399cat 478.267 kb on + strand, within Rv0399cat 479.497 kb on + strand, within Rv0400cat 479.498 kb on - strand, within Rv0400cat 479.498 kb on - strand, within Rv0400cat 479.498 kb on - strand, within Rv0400cat 479.761 kb on + strandat 480.314 kb on + strandat 480.336 kb on + strandat 480.498 kb on - strandat 480.704 kb on - strand, within Rv0402c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL
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477,566 - Rv0399c 0.19 -0.6
477,656 - Rv0399c 0.27 -0.4
478,152 + Rv0399c 0.67 -0.8
478,267 + Rv0399c 0.76 -2.0
479,497 + Rv0400c 0.78 -0.2
479,498 - Rv0400c 0.78 -0.3
479,498 - Rv0400c 0.78 -0.7
479,498 - Rv0400c 0.78 -0.4
479,761 + -0.7
480,314 + -0.2
480,336 + +0.4
480,498 - +1.0
480,704 - Rv0402c 0.12 -0.3

Or see this region's nucleotide sequence