Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0355c and Rv0356c are separated by 150 nucleotides Rv0356c and Rv0357c overlap by 4 nucleotides Rv0357c and Rv0358 are separated by 90 nucleotides Rv0358 and Rv0359 are separated by 10 nucleotides
Rv0355c: Rv0355c - PPE family protein PPE8, at 424,777 to 434,679
Rv0355c
Rv0356c: Rv0356c - Conserved protein, at 434,830 to 435,474
Rv0356c
Rv0357c: Rv0357c - Probable adenylosuccinate synthetase PurA (imp--aspartate ligase) (ADSS) (ampsase), at 435,471 to 436,769
Rv0357c
Rv0358: Rv0358 - Conserved protein, at 436,860 to 437,507
Rv0358
Rv0359: Rv0359 - Probable conserved integral membrane protein, at 437,518 to 438,297
Rv0359
Position (kb) 435
436
437 Strain fitness (log2 ratio) -2
-1
0
1 at 434.633 kb on + strand at 434.633 kb on + strand at 434.633 kb on + strand at 434.633 kb on + strand at 434.681 kb on + strand at 434.681 kb on + strand at 434.681 kb on + strand at 434.682 kb on - strand at 434.772 kb on + strand at 434.772 kb on + strand at 434.773 kb on - strand at 434.831 kb on + strand at 434.848 kb on + strand at 434.957 kb on - strand, within Rv0356c at 435.404 kb on + strand, within Rv0356c at 436.798 kb on - strand at 436.830 kb on - strand at 436.830 kb on - strand at 436.830 kb on - strand at 436.863 kb on + strand at 437.642 kb on - strand, within Rv0359 at 437.759 kb on - strand, within Rv0359
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 434,633 + +0.1 434,633 + -0.4 434,633 + +1.2 434,633 + -1.0 434,681 + -0.1 434,681 + +0.3 434,681 + +0.0 434,682 - -0.6 434,772 + +0.2 434,772 + +0.5 434,773 - -1.9 434,831 + -0.7 434,848 + +0.4 434,957 - Rv0356c 0.20 +0.2 435,404 + Rv0356c 0.89 +0.0 436,798 - -0.4 436,830 - -0.1 436,830 - +0.6 436,830 - +0.1 436,863 + -1.3 437,642 - Rv0359 0.16 +0.3 437,759 - Rv0359 0.31 +0.7
Or see this region's nucleotide sequence