Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0252 and Rv0253 are separated by 25 nucleotides Rv0253 and Rv0254c are separated by 15 nucleotides Rv0254c and Rv0255c are separated by 24 nucleotides Rv0255c and Rv0256c are separated by 18 nucleotides
Rv0252: Rv0252 - Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB, at 302,866 to 305,427
Rv0252
Rv0253: Rv0253 - Probable nitrite reductase [NAD(P)H] small subunit NirD, at 305,453 to 305,809
Rv0253
Rv0254c: Rv0254c - Probable bifunctional cobalamin biosynthesis protein CobU: cobinamide kinase + cobinamide phosphate guanylyltransferase, at 305,825 to 306,349
Rv0254c
Rv0255c: Rv0255c - Probable cobyric acid synthase CobQ1, at 306,374 to 307,858
Rv0255c
Rv0256c: Rv0256c - PPE family protein PPE2, at 307,877 to 309,547
Rv0256c
Position (kb) 306
307
308 Strain fitness (log2 ratio) -2
-1
0
1
2 at 305.406 kb on + strand at 305.406 kb on + strand at 305.479 kb on - strand at 305.753 kb on + strand, within Rv0253 at 305.808 kb on - strand at 305.861 kb on + strand at 305.861 kb on + strand at 306.039 kb on + strand, within Rv0254c at 306.817 kb on - strand, within Rv0255c at 306.817 kb on - strand, within Rv0255c at 306.911 kb on + strand, within Rv0255c at 306.912 kb on - strand, within Rv0255c at 307.131 kb on - strand, within Rv0255c at 307.188 kb on + strand, within Rv0255c at 307.189 kb on - strand, within Rv0255c at 307.189 kb on - strand, within Rv0255c at 307.261 kb on + strand, within Rv0255c at 307.750 kb on + strand at 307.816 kb on + strand at 307.817 kb on - strand at 308.075 kb on + strand, within Rv0256c at 308.268 kb on + strand, within Rv0256c at 308.268 kb on + strand, within Rv0256c at 308.283 kb on - strand, within Rv0256c at 308.283 kb on - strand, within Rv0256c at 308.674 kb on + strand, within Rv0256c at 308.754 kb on + strand, within Rv0256c at 308.754 kb on + strand, within Rv0256c at 308.754 kb on + strand, within Rv0256c at 308.754 kb on + strand, within Rv0256c at 308.754 kb on + strand, within Rv0256c at 308.755 kb on - strand, within Rv0256c at 308.755 kb on - strand, within Rv0256c at 308.755 kb on - strand, within Rv0256c at 308.816 kb on + strand, within Rv0256c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 305,406 + -0.2 305,406 + -0.6 305,479 - -0.1 305,753 + Rv0253 0.84 -0.1 305,808 - -0.6 305,861 + +0.5 305,861 + -0.3 306,039 + Rv0254c 0.41 +0.6 306,817 - Rv0255c 0.30 +0.7 306,817 - Rv0255c 0.30 +2.0 306,911 + Rv0255c 0.36 -0.2 306,912 - Rv0255c 0.36 +0.0 307,131 - Rv0255c 0.51 -0.9 307,188 + Rv0255c 0.55 +1.5 307,189 - Rv0255c 0.55 +2.0 307,189 - Rv0255c 0.55 +0.5 307,261 + Rv0255c 0.60 -0.0 307,750 + -0.3 307,816 + -0.3 307,817 - -1.1 308,075 + Rv0256c 0.12 -0.4 308,268 + Rv0256c 0.23 -0.3 308,268 + Rv0256c 0.23 +0.0 308,283 - Rv0256c 0.24 -1.0 308,283 - Rv0256c 0.24 -0.9 308,674 + Rv0256c 0.48 -0.5 308,754 + Rv0256c 0.52 -0.6 308,754 + Rv0256c 0.52 +0.4 308,754 + Rv0256c 0.52 -1.8 308,754 + Rv0256c 0.52 -0.0 308,754 + Rv0256c 0.52 -0.8 308,755 - Rv0256c 0.53 +0.5 308,755 - Rv0256c 0.53 +0.0 308,755 - Rv0256c 0.53 -1.2 308,816 + Rv0256c 0.56 -0.4
Or see this region's nucleotide sequence