Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0200 and Rv0201c overlap by 4 nucleotides Rv0201c and Rv0202c overlap by 4 nucleotides Rv0202c and Rv0203 are separated by 221 nucleotides Rv0203 and Rv0204c are separated by 51 nucleotides
Rv0200: Rv0200 - Possible conserved transmembrane protein, at 237,206 to 237,895
Rv0200
Rv0201c: Rv0201c - Conserved protein, at 237,892 to 238,395
Rv0201c
Rv0202c: Rv0202c - Probable conserved transmembrane transport protein MmpL11, at 238,392 to 241,292
Rv0202c
Rv0203: Rv0203 - Possible exported protein, at 241,514 to 241,924
Rv0203
Rv0204c: Rv0204c - Probable conserved transmembrane protein, at 241,976 to 243,214
Rv0204c
Position (kb)
238
239
240
241
242 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 237.659 kb on + strand, within Rv0200 at 237.659 kb on + strand, within Rv0200 at 237.659 kb on + strand, within Rv0200 at 238.123 kb on - strand, within Rv0201c at 238.243 kb on + strand, within Rv0201c at 238.300 kb on - strand, within Rv0201c at 238.573 kb on + strand at 238.623 kb on - strand at 238.961 kb on + strand, within Rv0202c at 238.961 kb on + strand, within Rv0202c at 239.302 kb on - strand, within Rv0202c at 239.392 kb on + strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.465 kb on - strand, within Rv0202c at 239.591 kb on - strand, within Rv0202c at 239.856 kb on + strand, within Rv0202c at 239.970 kb on - strand, within Rv0202c at 240.303 kb on + strand, within Rv0202c at 240.303 kb on + strand, within Rv0202c at 240.304 kb on - strand, within Rv0202c at 240.403 kb on + strand, within Rv0202c at 240.404 kb on - strand, within Rv0202c at 240.404 kb on - strand, within Rv0202c at 240.547 kb on + strand, within Rv0202c at 240.547 kb on + strand, within Rv0202c at 240.731 kb on + strand, within Rv0202c at 240.817 kb on + strand, within Rv0202c at 240.817 kb on + strand, within Rv0202c at 240.818 kb on - strand, within Rv0202c at 240.818 kb on - strand, within Rv0202c at 240.870 kb on + strand, within Rv0202c at 240.943 kb on + strand, within Rv0202c at 241.014 kb on + strand at 241.015 kb on - strand at 241.055 kb on - strand at 241.058 kb on + strand at 241.059 kb on - strand at 241.059 kb on - strand at 241.183 kb on - strand at 241.210 kb on + strand at 241.210 kb on + strand at 241.348 kb on - strand at 241.558 kb on - strand, within Rv0203 at 241.691 kb on + strand, within Rv0203 at 241.692 kb on - strand, within Rv0203 at 241.799 kb on - strand, within Rv0203 at 241.923 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 237,659 + Rv0200 0.66 -1.1 237,659 + Rv0200 0.66 +2.0 237,659 + Rv0200 0.66 -0.0 238,123 - Rv0201c 0.46 +0.2 238,243 + Rv0201c 0.70 -0.9 238,300 - Rv0201c 0.81 -1.1 238,573 + -0.3 238,623 - -1.6 238,961 + Rv0202c 0.20 -1.4 238,961 + Rv0202c 0.20 -1.4 239,302 - Rv0202c 0.31 -3.6 239,392 + Rv0202c 0.34 -1.4 239,465 - Rv0202c 0.37 -1.4 239,465 - Rv0202c 0.37 -1.3 239,465 - Rv0202c 0.37 -1.1 239,591 - Rv0202c 0.41 -1.0 239,856 + Rv0202c 0.50 +0.9 239,970 - Rv0202c 0.54 -1.8 240,303 + Rv0202c 0.66 -1.6 240,303 + Rv0202c 0.66 -2.1 240,304 - Rv0202c 0.66 -0.7 240,403 + Rv0202c 0.69 -1.8 240,404 - Rv0202c 0.69 -1.7 240,404 - Rv0202c 0.69 -1.6 240,547 + Rv0202c 0.74 -1.9 240,547 + Rv0202c 0.74 -2.4 240,731 + Rv0202c 0.81 -2.3 240,817 + Rv0202c 0.84 -3.2 240,817 + Rv0202c 0.84 -2.9 240,818 - Rv0202c 0.84 -2.7 240,818 - Rv0202c 0.84 -0.2 240,870 + Rv0202c 0.85 -0.0 240,943 + Rv0202c 0.88 -1.6 241,014 + -1.9 241,015 - +1.2 241,055 - -1.3 241,058 + -1.7 241,059 - -0.6 241,059 - -1.2 241,183 - -1.7 241,210 + -0.6 241,210 + -1.6 241,348 - +0.4 241,558 - Rv0203 0.11 -0.1 241,691 + Rv0203 0.43 -0.4 241,692 - Rv0203 0.43 -0.4 241,799 - Rv0203 0.69 +0.1 241,923 - -0.6
Or see this region's nucleotide sequence