Experiment: 7H9 with Clofazimine 0.072 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0136 and Rv0137c are separated by 20 nucleotides Rv0137c and Rv0138 are separated by 62 nucleotides Rv0138 and Rv0139 are separated by 0 nucleotides
Rv0136: Rv0136 - Probable cytochrome P450 138 Cyp138, at 163,366 to 164,691
Rv0136
Rv0137c: Rv0137c - Probable peptide methionine sulfoxide reductase MsrA (protein-methionine-S-oxide reductase) (peptide met(O) reductase), at 164,712 to 165,260
Rv0137c
Rv0138: Rv0138 - Conserved hypothetical protein, at 165,323 to 165,826
Rv0138
Rv0139: Rv0139 - Possible oxidoreductase, at 165,827 to 166,849
Rv0139
Position (kb) 165
166 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 164.354 kb on - strand, within Rv0136 at 164.397 kb on + strand, within Rv0136 at 164.404 kb on - strand, within Rv0136 at 164.414 kb on + strand, within Rv0136 at 164.414 kb on + strand, within Rv0136 at 164.414 kb on + strand, within Rv0136 at 164.415 kb on - strand, within Rv0136 at 164.478 kb on + strand, within Rv0136 at 164.831 kb on - strand, within Rv0137c at 164.968 kb on + strand, within Rv0137c at 164.969 kb on - strand, within Rv0137c at 165.005 kb on + strand, within Rv0137c at 165.006 kb on - strand, within Rv0137c at 165.130 kb on + strand, within Rv0137c at 165.130 kb on + strand, within Rv0137c at 165.130 kb on + strand, within Rv0137c at 165.160 kb on + strand, within Rv0137c at 165.161 kb on - strand, within Rv0137c at 165.282 kb on + strand at 165.283 kb on - strand at 165.283 kb on - strand at 165.283 kb on - strand at 165.303 kb on - strand at 165.303 kb on - strand at 165.434 kb on + strand, within Rv0138 at 165.434 kb on + strand, within Rv0138 at 165.435 kb on - strand, within Rv0138 at 165.435 kb on - strand, within Rv0138 at 165.674 kb on + strand, within Rv0138 at 165.674 kb on + strand, within Rv0138 at 165.674 kb on + strand, within Rv0138 at 165.674 kb on + strand, within Rv0138 at 165.674 kb on + strand, within Rv0138 at 165.675 kb on - strand, within Rv0138 at 165.675 kb on - strand, within Rv0138 at 165.675 kb on - strand, within Rv0138 at 165.713 kb on + strand, within Rv0138 at 165.713 kb on + strand, within Rv0138 at 165.713 kb on + strand, within Rv0138 at 165.713 kb on + strand, within Rv0138 at 165.713 kb on + strand, within Rv0138 at 165.714 kb on - strand, within Rv0138 at 165.714 kb on - strand, within Rv0138 at 165.714 kb on - strand, within Rv0138 at 165.824 kb on + strand at 165.824 kb on + strand at 165.824 kb on + strand at 165.924 kb on + strand at 165.925 kb on - strand at 166.049 kb on + strand, within Rv0139 at 166.049 kb on + strand, within Rv0139 at 166.049 kb on + strand, within Rv0139 at 166.049 kb on + strand, within Rv0139 at 166.050 kb on - strand, within Rv0139 at 166.050 kb on - strand, within Rv0139 at 166.050 kb on - strand, within Rv0139 at 166.050 kb on - strand, within Rv0139 at 166.050 kb on - strand, within Rv0139 at 166.053 kb on - strand, within Rv0139 at 166.184 kb on + strand, within Rv0139 at 166.259 kb on + strand, within Rv0139 at 166.259 kb on + strand, within Rv0139 at 166.259 kb on + strand, within Rv0139 at 166.260 kb on - strand, within Rv0139 at 166.260 kb on - strand, within Rv0139 at 166.302 kb on - strand, within Rv0139 at 166.352 kb on + strand, within Rv0139 at 166.353 kb on - strand, within Rv0139 at 166.520 kb on + strand, within Rv0139 at 166.520 kb on + strand, within Rv0139 at 166.521 kb on - strand, within Rv0139 at 166.521 kb on - strand, within Rv0139 at 166.521 kb on - strand, within Rv0139 at 166.676 kb on - strand, within Rv0139
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Clofazimine 0.072 ug/mL remove 164,354 - Rv0136 0.75 -1.5 164,397 + Rv0136 0.78 +1.0 164,404 - Rv0136 0.78 +2.0 164,414 + Rv0136 0.79 -0.6 164,414 + Rv0136 0.79 -2.2 164,414 + Rv0136 0.79 +0.3 164,415 - Rv0136 0.79 -0.1 164,478 + Rv0136 0.84 +1.1 164,831 - Rv0137c 0.22 -1.0 164,968 + Rv0137c 0.47 +0.2 164,969 - Rv0137c 0.47 -0.2 165,005 + Rv0137c 0.53 +0.0 165,006 - Rv0137c 0.54 +0.2 165,130 + Rv0137c 0.76 +2.0 165,130 + Rv0137c 0.76 -1.1 165,130 + Rv0137c 0.76 +0.1 165,160 + Rv0137c 0.82 +1.6 165,161 - Rv0137c 0.82 -0.5 165,282 + -0.0 165,283 - +2.0 165,283 - -0.2 165,283 - -0.3 165,303 - -0.1 165,303 - +0.3 165,434 + Rv0138 0.22 +0.1 165,434 + Rv0138 0.22 +1.0 165,435 - Rv0138 0.22 -0.1 165,435 - Rv0138 0.22 +0.7 165,674 + Rv0138 0.70 +0.4 165,674 + Rv0138 0.70 +0.3 165,674 + Rv0138 0.70 -0.5 165,674 + Rv0138 0.70 -0.0 165,674 + Rv0138 0.70 -0.2 165,675 - Rv0138 0.70 +2.0 165,675 - Rv0138 0.70 -0.5 165,675 - Rv0138 0.70 +0.2 165,713 + Rv0138 0.77 +0.4 165,713 + Rv0138 0.77 -0.7 165,713 + Rv0138 0.77 -0.1 165,713 + Rv0138 0.77 +1.7 165,713 + Rv0138 0.77 +1.3 165,714 - Rv0138 0.78 +1.0 165,714 - Rv0138 0.78 -0.4 165,714 - Rv0138 0.78 +0.1 165,824 + +0.5 165,824 + +1.0 165,824 + -1.5 165,924 + -0.9 165,925 - +0.4 166,049 + Rv0139 0.22 -0.5 166,049 + Rv0139 0.22 -0.3 166,049 + Rv0139 0.22 +1.4 166,049 + Rv0139 0.22 -0.3 166,050 - Rv0139 0.22 -0.6 166,050 - Rv0139 0.22 +0.8 166,050 - Rv0139 0.22 -0.4 166,050 - Rv0139 0.22 +3.0 166,050 - Rv0139 0.22 +0.1 166,053 - Rv0139 0.22 +2.5 166,184 + Rv0139 0.35 -0.7 166,259 + Rv0139 0.42 +0.9 166,259 + Rv0139 0.42 +0.0 166,259 + Rv0139 0.42 +0.2 166,260 - Rv0139 0.42 +1.0 166,260 - Rv0139 0.42 -0.5 166,302 - Rv0139 0.46 +0.2 166,352 + Rv0139 0.51 -0.1 166,353 - Rv0139 0.51 -0.0 166,520 + Rv0139 0.68 +0.4 166,520 + Rv0139 0.68 +0.2 166,521 - Rv0139 0.68 +0.5 166,521 - Rv0139 0.68 -0.1 166,521 - Rv0139 0.68 -0.0 166,676 - Rv0139 0.83 +0.1
Or see this region's nucleotide sequence