Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3890c

Experiment: 7H9 with Linezolid 0.44 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.44 ug/mL
4,372,823	-				-0.3
4,372,823	-				-1.5
4,373,091	+		Rv3889c	0.35	-0.5
4,373,091	+		Rv3889c	0.35	+0.1
4,373,091	+		Rv3889c	0.35	-1.3
4,373,092	-		Rv3889c	0.35	-0.7
4,373,125	+		Rv3889c	0.39	-0.1
4,373,151	+		Rv3889c	0.42	-0.2
4,373,160	+		Rv3889c	0.43	+1.0
4,373,160	+		Rv3889c	0.43	+0.4
4,373,161	-		Rv3889c	0.43	-0.4
4,373,163	+		Rv3889c	0.44	-0.2
4,373,163	+		Rv3889c	0.44	-0.2
4,373,164	-		Rv3889c	0.44	-1.0
4,373,164	-		Rv3889c	0.44	-0.5
4,373,164	-		Rv3889c	0.44	-0.7
4,373,164	-		Rv3889c	0.44	-0.4
4,373,287	+		Rv3889c	0.59	+0.5
4,373,395	-		Rv3889c	0.72	-0.0
4,373,551	-				-0.5
4,373,595	+				-0.6
4,373,595	+				+2.1
4,373,595	+				+0.1
4,373,596	-				-0.7
4,373,599	-				-1.1
4,373,652	+				+0.8
4,373,652	+				+0.7
4,373,652	+				-0.8
4,373,695	+				+0.2
4,373,727	+				+3.0
4,373,728	-				-0.4
4,373,788	+		Rv3890c	0.22	-0.4
4,373,789	-		Rv3890c	0.22	+0.1
4,373,789	-		Rv3890c	0.22	+0.1
4,373,925	+		Rv3890c	0.69	-1.0
4,373,925	+		Rv3890c	0.69	-0.0
4,373,926	-		Rv3890c	0.69	-0.3
4,373,969	+		Rv3890c	0.84	+0.8
4,373,993	-				-0.6
4,373,994	+				+0.0
4,373,994	+				+0.2
4,373,994	+				-0.3
4,373,995	-				-0.3
4,373,995	-				-0.2
4,374,208	-		Rv3891c	0.49	+1.8
4,374,208	-		Rv3891c	0.49	-0.6
4,374,272	-		Rv3891c	0.69	-0.5
4,374,272	-		Rv3891c	0.69	-0.4
4,374,276	-		Rv3891c	0.70	-0.4
4,374,414	+				+1.8
4,374,436	+				-0.7
4,374,436	+				-0.3
4,374,437	-				+1.5
4,374,437	-				-0.6
4,374,437	-				-1.6
4,374,437	-				-0.7
4,374,479	+				-0.6