Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2589

Experiment: 7H9 with Linezolid 0.44 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Linezolid 0.44 ug/mL
2,915,746	-				-1.6
2,915,769	-				-0.5
2,915,784	+				-0.2
2,915,784	+				-1.0
2,915,784	+				-0.5
2,915,784	+				-0.3
2,915,784	+				-0.2
2,915,784	+				-0.2
2,915,784	+				-0.7
2,915,785	-				+0.8
2,915,785	-				-0.2
2,915,785	-				+0.3
2,915,785	-				-0.1
2,915,785	-				+0.1
2,915,785	-				-0.1
2,916,059	+		Rv2588c	0.61	+1.1
2,916,138	+		Rv2588c	0.84	+0.9
2,916,138	+		Rv2588c	0.84	+1.4
2,916,138	+		Rv2588c	0.84	+0.2
2,916,139	-		Rv2588c	0.84	+0.1
2,916,208	+				-0.2
2,916,209	-				+0.8
2,916,209	-				-0.9
2,916,209	-				+0.3
2,916,209	-				+0.5
2,916,215	-				+0.8
2,916,215	-				+0.7
2,916,259	+				-0.5
2,916,259	+				+1.8
2,916,313	+				-0.3
2,916,624	-		Rv2589	0.20	+0.0
2,916,651	+		Rv2589	0.22	+0.0
2,916,660	+		Rv2589	0.22	+1.0
2,916,660	+		Rv2589	0.22	-0.1
2,916,661	-		Rv2589	0.22	-1.2
2,916,661	-		Rv2589	0.22	-0.0
2,916,661	-		Rv2589	0.22	+1.2
2,916,661	-		Rv2589	0.22	+1.3
2,916,661	-		Rv2589	0.22	-0.6
2,916,661	-		Rv2589	0.22	+0.1
2,916,692	+		Rv2589	0.25	-0.8
2,916,778	-		Rv2589	0.31	+0.1
2,916,816	+		Rv2589	0.34	-1.4
2,916,816	+		Rv2589	0.34	+0.1
2,916,816	+		Rv2589	0.34	+0.0
2,916,835	+		Rv2589	0.35	-0.8
2,916,836	-		Rv2589	0.35	-0.3
2,916,867	+		Rv2589	0.38	-0.3
2,916,868	-		Rv2589	0.38	-1.6
2,916,868	-		Rv2589	0.38	+0.1
2,916,868	-		Rv2589	0.38	+0.3
2,916,868	-		Rv2589	0.38	-0.1
2,916,922	-		Rv2589	0.42	+0.2
2,916,922	-		Rv2589	0.42	-0.5
2,916,922	-		Rv2589	0.42	-0.0
2,916,959	+		Rv2589	0.44	-1.4
2,916,973	+		Rv2589	0.45	-0.2
2,917,013	-		Rv2589	0.48	-0.2
2,917,094	-		Rv2589	0.54	-0.7
2,917,094	-		Rv2589	0.54	-1.0
2,917,508	-		Rv2589	0.85	+0.2
2,917,630	+				+0.4
2,917,782	-				-0.1
2,917,784	+				-0.1
2,917,914	+				-0.5
2,917,914	+				-0.3
2,917,914	+				+1.8
2,917,914	+				-1.1
2,917,914	+				-0.5
2,917,914	+				-0.5
2,917,914	+				-0.3
2,917,914	+				+1.8
2,917,915	-				-0.5
2,917,915	-				-0.4
2,917,915	-				+0.2
2,917,915	-				-0.0
2,917,917	-				+0.7
2,917,917	-				-0.0
2,918,012	-				+0.1
2,918,106	+				-0.8
2,918,106	+				-0.2
2,918,106	+				-0.4
2,918,107	-				-0.7
2,918,107	-				+0.5
2,918,107	-				-0.8
2,918,428	-		Rv2590	0.16	-2.0
2,918,428	-		Rv2590	0.16	-0.6
2,918,600	+		Rv2590	0.21	-0.2
2,918,600	+		Rv2590	0.21	+0.4
2,918,601	-		Rv2590	0.21	-0.5
2,918,611	+		Rv2590	0.21	+1.5
2,918,611	+		Rv2590	0.21	+0.5
2,918,611	+		Rv2590	0.21	+0.2
2,918,615	-		Rv2590	0.21	-0.7