Experiment: 7H9 with Linezolid 0.44 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2090 and Rv2091c are separated by 3 nucleotides Rv2091c and Rv2092c are separated by 41 nucleotides Rv2092c and Rv2093c are separated by 48 nucleotides Rv2093c and Rv2094c are separated by 16 nucleotides
Rv2090: Rv2090 - Probable 5'-3' exonuclease, at 2,347,373 to 2,348,554
Rv2090
Rv2091c: Rv2091c - Probable membrane protein, at 2,348,558 to 2,349,292
Rv2091c
Rv2092c: Rv2092c - ATP-dependent DNA helicase HelY, at 2,349,334 to 2,352,054
Rv2092c
Rv2093c: Rv2093c - Sec-independent protein translocase transmembrane protein TatC, at 2,352,103 to 2,353,029
Rv2093c
Rv2094c: Rv2094c - Sec-independent protein translocase membrane-bound protein TatA, at 2,353,046 to 2,353,297
Rv2094c
Position (kb)
2349
2350
2351
2352
2353 Strain fitness (log2 ratio)
-1
0
1
2 at 2348.340 kb on + strand, within Rv2090 at 2348.340 kb on + strand, within Rv2090 at 2348.340 kb on + strand, within Rv2090 at 2348.341 kb on - strand, within Rv2090 at 2348.345 kb on - strand, within Rv2090 at 2348.345 kb on - strand, within Rv2090 at 2348.345 kb on - strand, within Rv2090 at 2348.345 kb on - strand, within Rv2090 at 2348.370 kb on - strand, within Rv2090 at 2348.560 kb on - strand at 2348.560 kb on - strand at 2348.580 kb on + strand at 2348.580 kb on + strand at 2348.581 kb on - strand at 2348.773 kb on + strand, within Rv2091c at 2348.829 kb on - strand, within Rv2091c at 2348.919 kb on + strand, within Rv2091c at 2348.976 kb on + strand, within Rv2091c at 2348.976 kb on + strand, within Rv2091c at 2348.994 kb on + strand, within Rv2091c at 2349.012 kb on + strand, within Rv2091c at 2349.021 kb on + strand, within Rv2091c at 2349.021 kb on + strand, within Rv2091c at 2349.022 kb on - strand, within Rv2091c at 2349.135 kb on + strand, within Rv2091c at 2349.320 kb on - strand at 2349.378 kb on + strand at 2349.734 kb on + strand, within Rv2092c at 2349.734 kb on + strand, within Rv2092c at 2349.735 kb on - strand, within Rv2092c at 2349.795 kb on + strand, within Rv2092c at 2349.795 kb on + strand, within Rv2092c at 2349.799 kb on + strand, within Rv2092c at 2349.799 kb on + strand, within Rv2092c at 2349.976 kb on + strand, within Rv2092c at 2350.003 kb on + strand, within Rv2092c at 2350.003 kb on + strand, within Rv2092c at 2350.004 kb on - strand, within Rv2092c at 2350.004 kb on - strand, within Rv2092c at 2350.007 kb on + strand, within Rv2092c at 2350.008 kb on - strand, within Rv2092c at 2350.050 kb on + strand, within Rv2092c at 2350.050 kb on + strand, within Rv2092c at 2350.050 kb on + strand, within Rv2092c at 2350.051 kb on - strand, within Rv2092c at 2350.051 kb on - strand, within Rv2092c at 2350.143 kb on + strand, within Rv2092c at 2350.143 kb on + strand, within Rv2092c at 2350.143 kb on + strand, within Rv2092c at 2350.144 kb on - strand, within Rv2092c at 2350.300 kb on + strand, within Rv2092c at 2350.502 kb on + strand, within Rv2092c at 2350.555 kb on + strand, within Rv2092c at 2350.555 kb on + strand, within Rv2092c at 2350.841 kb on + strand, within Rv2092c at 2350.841 kb on + strand, within Rv2092c at 2350.842 kb on - strand, within Rv2092c at 2350.842 kb on - strand, within Rv2092c at 2351.047 kb on + strand, within Rv2092c at 2351.067 kb on - strand, within Rv2092c at 2351.067 kb on - strand, within Rv2092c at 2351.070 kb on - strand, within Rv2092c at 2351.291 kb on + strand, within Rv2092c at 2351.706 kb on - strand, within Rv2092c at 2351.861 kb on + strand at 2351.862 kb on - strand at 2351.872 kb on - strand at 2352.013 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.44 ug/mL remove 2,348,340 + Rv2090 0.82 -0.5 2,348,340 + Rv2090 0.82 -0.6 2,348,340 + Rv2090 0.82 -0.2 2,348,341 - Rv2090 0.82 -0.6 2,348,345 - Rv2090 0.82 -0.1 2,348,345 - Rv2090 0.82 +0.2 2,348,345 - Rv2090 0.82 +0.1 2,348,345 - Rv2090 0.82 -1.0 2,348,370 - Rv2090 0.84 -0.2 2,348,560 - +1.3 2,348,560 - +2.4 2,348,580 + -0.3 2,348,580 + -0.1 2,348,581 - -0.0 2,348,773 + Rv2091c 0.29 -1.1 2,348,829 - Rv2091c 0.37 +1.7 2,348,919 + Rv2091c 0.49 -0.3 2,348,976 + Rv2091c 0.57 +0.2 2,348,976 + Rv2091c 0.57 +1.3 2,348,994 + Rv2091c 0.59 -0.2 2,349,012 + Rv2091c 0.62 +0.3 2,349,021 + Rv2091c 0.63 -0.6 2,349,021 + Rv2091c 0.63 +0.4 2,349,022 - Rv2091c 0.63 -0.6 2,349,135 + Rv2091c 0.79 +0.1 2,349,320 - +0.1 2,349,378 + +0.6 2,349,734 + Rv2092c 0.15 +2.2 2,349,734 + Rv2092c 0.15 +0.5 2,349,735 - Rv2092c 0.15 +0.2 2,349,795 + Rv2092c 0.17 +0.8 2,349,795 + Rv2092c 0.17 +0.0 2,349,799 + Rv2092c 0.17 -0.3 2,349,799 + Rv2092c 0.17 +0.6 2,349,976 + Rv2092c 0.24 -0.7 2,350,003 + Rv2092c 0.25 +2.7 2,350,003 + Rv2092c 0.25 +0.1 2,350,004 - Rv2092c 0.25 +1.0 2,350,004 - Rv2092c 0.25 +1.4 2,350,007 + Rv2092c 0.25 +1.0 2,350,008 - Rv2092c 0.25 +1.1 2,350,050 + Rv2092c 0.26 +0.7 2,350,050 + Rv2092c 0.26 -0.1 2,350,050 + Rv2092c 0.26 +1.7 2,350,051 - Rv2092c 0.26 +1.7 2,350,051 - Rv2092c 0.26 +1.2 2,350,143 + Rv2092c 0.30 +0.5 2,350,143 + Rv2092c 0.30 +0.6 2,350,143 + Rv2092c 0.30 +1.4 2,350,144 - Rv2092c 0.30 +0.6 2,350,300 + Rv2092c 0.36 +0.2 2,350,502 + Rv2092c 0.43 +0.3 2,350,555 + Rv2092c 0.45 -0.2 2,350,555 + Rv2092c 0.45 +1.6 2,350,841 + Rv2092c 0.55 +0.4 2,350,841 + Rv2092c 0.55 -0.0 2,350,842 - Rv2092c 0.55 +0.5 2,350,842 - Rv2092c 0.55 +0.9 2,351,047 + Rv2092c 0.63 -1.6 2,351,067 - Rv2092c 0.64 +0.6 2,351,067 - Rv2092c 0.64 +1.3 2,351,070 - Rv2092c 0.64 +2.5 2,351,291 + Rv2092c 0.72 +1.7 2,351,706 - Rv2092c 0.87 +0.9 2,351,861 + +2.7 2,351,862 - +1.7 2,351,872 - +1.6 2,352,013 + +0.7
Or see this region's nucleotide sequence