Experiment: 7H9 with Linezolid 0.44 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0633c and Rv0634c are separated by 153 nucleotides Rv0634c and Rv0634A are separated by 79 nucleotides Rv0634A and GFF660 are separated by 129 nucleotides GFF660 and GFF661 are separated by 36 nucleotides GFF661 and Rv0634B are separated by 35 nucleotides Rv0634B and Rv0635 are separated by 50 nucleotides
Rv0633c: Rv0633c - Possible exported protein, at 729,327 to 730,166
Rv0633c
Rv0634c: Rv0634c - Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II), at 730,320 to 731,033
Rv0634c
Rv0634A: Rv0634A - Unknown protein, at 731,113 to 731,364
Rv0634A
GFF660 - tRNA-Thr, at 731,494 to 731,566
GFF660
GFF661 - tRNA-Met, at 731,603 to 731,676
GFF661
Rv0634B: Rv0634B - 50S ribosomal protein L33 RpmG2, at 731,712 to 731,879
Rv0634B
Rv0635: Rv0635 - (3R)-hydroxyacyl-ACP dehydratase subunit HadA, at 731,930 to 732,406
Rv0635
Position (kb) 730
731
732 Strain fitness (log2 ratio) -2
-1
0
1
2 at 729.328 kb on + strand at 729.508 kb on + strand, within Rv0633c at 729.508 kb on + strand, within Rv0633c at 729.521 kb on + strand, within Rv0633c at 729.522 kb on - strand, within Rv0633c at 729.522 kb on - strand, within Rv0633c at 729.522 kb on - strand, within Rv0633c at 729.525 kb on + strand, within Rv0633c at 729.526 kb on - strand, within Rv0633c at 729.691 kb on + strand, within Rv0633c at 729.692 kb on - strand, within Rv0633c at 729.694 kb on + strand, within Rv0633c at 729.695 kb on - strand, within Rv0633c at 729.838 kb on + strand, within Rv0633c at 729.905 kb on - strand, within Rv0633c at 729.934 kb on - strand, within Rv0633c at 729.989 kb on - strand, within Rv0633c at 729.989 kb on - strand, within Rv0633c at 730.172 kb on + strand at 730.173 kb on - strand at 730.173 kb on - strand at 730.173 kb on - strand at 730.174 kb on + strand at 730.201 kb on + strand at 730.372 kb on + strand at 730.372 kb on + strand at 730.373 kb on - strand at 730.484 kb on - strand, within Rv0634c at 730.539 kb on + strand, within Rv0634c at 730.539 kb on + strand, within Rv0634c at 730.540 kb on - strand, within Rv0634c at 730.737 kb on + strand, within Rv0634c at 730.738 kb on - strand, within Rv0634c at 730.848 kb on - strand, within Rv0634c at 730.889 kb on - strand, within Rv0634c at 730.889 kb on - strand, within Rv0634c at 731.014 kb on + strand at 731.015 kb on - strand at 731.015 kb on - strand at 731.044 kb on + strand at 731.044 kb on + strand at 731.045 kb on - strand at 731.101 kb on + strand at 731.101 kb on + strand at 731.102 kb on - strand at 731.102 kb on - strand at 731.171 kb on + strand, within Rv0634A at 731.305 kb on + strand, within Rv0634A at 731.305 kb on + strand, within Rv0634A at 731.306 kb on - strand, within Rv0634A at 731.394 kb on + strand at 731.394 kb on + strand at 731.912 kb on + strand at 731.912 kb on + strand at 731.916 kb on + strand at 731.916 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.44 ug/mL remove 729,328 + -1.4 729,508 + Rv0633c 0.22 -0.3 729,508 + Rv0633c 0.22 -0.4 729,521 + Rv0633c 0.23 -0.1 729,522 - Rv0633c 0.23 +0.4 729,522 - Rv0633c 0.23 +0.3 729,522 - Rv0633c 0.23 -1.1 729,525 + Rv0633c 0.24 +0.2 729,526 - Rv0633c 0.24 -0.3 729,691 + Rv0633c 0.43 -0.9 729,692 - Rv0633c 0.43 -0.8 729,694 + Rv0633c 0.44 -0.3 729,695 - Rv0633c 0.44 +0.2 729,838 + Rv0633c 0.61 -0.4 729,905 - Rv0633c 0.69 -0.5 729,934 - Rv0633c 0.72 -0.0 729,989 - Rv0633c 0.79 +0.0 729,989 - Rv0633c 0.79 -0.6 730,172 + -0.0 730,173 - -0.6 730,173 - -0.4 730,173 - -0.3 730,174 + +1.0 730,201 + +1.8 730,372 + +1.0 730,372 + -0.1 730,373 - -0.6 730,484 - Rv0634c 0.23 +0.0 730,539 + Rv0634c 0.31 -0.0 730,539 + Rv0634c 0.31 +0.8 730,540 - Rv0634c 0.31 -0.0 730,737 + Rv0634c 0.58 +0.6 730,738 - Rv0634c 0.59 +0.3 730,848 - Rv0634c 0.74 +1.1 730,889 - Rv0634c 0.80 +0.5 730,889 - Rv0634c 0.80 +0.8 731,014 + +0.5 731,015 - -0.2 731,015 - +0.3 731,044 + +0.2 731,044 + +0.1 731,045 - +0.7 731,101 + -0.9 731,101 + +0.1 731,102 - -0.2 731,102 - -2.3 731,171 + Rv0634A 0.23 +0.1 731,305 + Rv0634A 0.76 +0.5 731,305 + Rv0634A 0.76 +0.0 731,306 - Rv0634A 0.77 +0.3 731,394 + -2.5 731,394 + -0.2 731,912 + +1.8 731,912 + +1.8 731,916 + -0.5 731,916 + -0.5
Or see this region's nucleotide sequence