Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0614

Experiment: 7H9 with Linezolid 0.44 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0613c and Rv0614 overlap by 160 nucleotidesRv0614 and Rv0615 overlap by 4 nucleotidesRv0615 and Rv0616c overlap by 4 nucleotidesRv0616c and Rv0616A overlap by 69 nucleotidesRv0616A and Rv0617 overlap by 4 nucleotides Rv0613c: Rv0613c - Unknown protein, at 706,948 to 709,515 Rv0613c Rv0614: Rv0614 - Conserved hypothetical protein, at 709,356 to 710,348 Rv0614 Rv0615: Rv0615 - Probable integral membrane protein, at 710,345 to 710,587 Rv0615 Rv0616c: Rv0616c - Hypothetical protein, at 710,584 to 710,850 Rv0616c Rv0616A: Rv0616A - Possible antitoxin VapB29, at 710,782 to 711,009 Rv0616A Rv0617: Rv0617 - Possible toxin VapC29. Contains PIN domain., at 711,006 to 711,407 Rv0617 Position (kb) 709 710 711Strain fitness (log2 ratio) -1 0 1 2at 708.705 kb on - strand, within Rv0613cat 708.705 kb on - strand, within Rv0613cat 709.202 kb on + strand, within Rv0613cat 709.300 kb on + strandat 709.301 kb on - strandat 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.527 kb on + strand, within Rv0614at 709.528 kb on - strand, within Rv0614at 709.750 kb on + strand, within Rv0614at 709.751 kb on - strand, within Rv0614at 709.991 kb on + strand, within Rv0614at 710.028 kb on - strand, within Rv0614at 710.071 kb on + strand, within Rv0614at 710.072 kb on - strand, within Rv0614at 710.157 kb on + strand, within Rv0614at 710.323 kb on + strandat 710.323 kb on + strandat 710.355 kb on + strandat 710.355 kb on + strandat 710.435 kb on + strand, within Rv0615at 710.436 kb on - strand, within Rv0615at 710.586 kb on - strandat 710.790 kb on + strandat 710.790 kb on + strandat 710.993 kb on + strandat 711.300 kb on + strand, within Rv0617at 711.301 kb on - strand, within Rv0617at 711.301 kb on - strand, within Rv0617

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Linezolid 0.44 ug/mL
remove
708,705 - Rv0613c 0.68 -0.0
708,705 - Rv0613c 0.68 +0.5
709,202 + Rv0613c 0.88 +1.4
709,300 + -1.4
709,301 - -1.1
709,527 + Rv0614 0.17 -0.2
709,527 + Rv0614 0.17 -0.2
709,527 + Rv0614 0.17 +0.2
709,527 + Rv0614 0.17 -0.3
709,528 - Rv0614 0.17 +1.8
709,750 + Rv0614 0.40 +0.4
709,751 - Rv0614 0.40 +0.2
709,991 + Rv0614 0.64 -0.3
710,028 - Rv0614 0.68 -0.3
710,071 + Rv0614 0.72 +1.0
710,072 - Rv0614 0.72 +0.4
710,157 + Rv0614 0.81 -0.4
710,323 + +0.0
710,323 + -0.8
710,355 + -0.4
710,355 + -0.3
710,435 + Rv0615 0.37 -0.3
710,436 - Rv0615 0.37 -1.1
710,586 - -0.1
710,790 + +1.4
710,790 + -0.2
710,993 + +0.2
711,300 + Rv0617 0.73 +1.8
711,301 - Rv0617 0.73 -0.9
711,301 - Rv0617 0.73 +0.8

Or see this region's nucleotide sequence