Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3823c

Experiment: 7H9 with Ethambutol 0.75 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethambutol 0.75 ug/mL
4,287,288	-		Rv3822	0.47	+0.4
4,287,399	+		Rv3822	0.56	-0.5
4,287,400	-		Rv3822	0.56	-0.1
4,287,440	-		Rv3822	0.59	-2.4
4,287,477	+		Rv3822	0.62	+0.1
4,287,477	+		Rv3822	0.62	-0.2
4,287,478	-		Rv3822	0.62	-0.5
4,287,478	-		Rv3822	0.62	-0.4
4,287,533	+		Rv3822	0.67	-0.5
4,287,533	+		Rv3822	0.67	-0.8
4,287,533	+		Rv3822	0.67	+0.2
4,287,573	+		Rv3822	0.70	-0.7
4,287,574	-		Rv3822	0.70	-1.0
4,287,574	-		Rv3822	0.70	-0.4
4,287,574	-		Rv3822	0.70	-1.7
4,287,574	-		Rv3822	0.70	-0.9
4,287,574	-		Rv3822	0.70	-0.2
4,287,596	-		Rv3822	0.72	+0.3
4,287,596	-		Rv3822	0.72	+1.9
4,287,690	+		Rv3822	0.80	-0.7
4,287,690	+		Rv3822	0.80	+0.1
4,287,980	+				-0.8
4,287,980	+				+0.1
4,288,231	+				+1.9
4,288,232	-				-0.1
4,288,261	+				-0.2
4,288,262	-				-0.2
4,288,262	-				+1.9
4,288,352	+				-0.3
4,288,353	-				+1.9
4,288,479	-				+0.5
4,288,567	+				-0.7
4,288,568	-				+0.4
4,288,568	-				-0.7
4,288,568	-				+0.6
4,288,837	+		Rv3823c	0.18	-0.6
4,288,838	-		Rv3823c	0.18	-0.8
4,289,166	+		Rv3823c	0.28	+0.3
4,289,166	+		Rv3823c	0.28	-0.8
4,289,225	-		Rv3823c	0.30	+0.3
4,289,247	-		Rv3823c	0.30	+0.7
4,289,249	-		Rv3823c	0.30	-0.9
4,289,249	-		Rv3823c	0.30	-1.3
4,289,249	-		Rv3823c	0.30	-1.0
4,289,249	-		Rv3823c	0.30	-0.6
4,289,295	+		Rv3823c	0.32	-0.6
4,289,568	+		Rv3823c	0.40	-1.0
4,289,827	+		Rv3823c	0.48	-1.1
4,289,828	-		Rv3823c	0.48	-1.2
4,289,828	-		Rv3823c	0.48	-1.8
4,290,109	-		Rv3823c	0.57	-0.6
4,290,109	-		Rv3823c	0.57	-1.6
4,290,163	+		Rv3823c	0.58	-0.6
4,290,163	+		Rv3823c	0.58	+1.9
4,290,182	+		Rv3823c	0.59	-2.4
4,290,212	-		Rv3823c	0.60	-0.5
4,290,212	-		Rv3823c	0.60	-1.1
4,290,259	+		Rv3823c	0.61	-1.1
4,290,259	+		Rv3823c	0.61	-0.9
4,290,260	-		Rv3823c	0.61	-1.2
4,290,260	-		Rv3823c	0.61	-0.7
4,290,260	-		Rv3823c	0.61	-2.0
4,290,260	-		Rv3823c	0.61	-1.4
4,290,297	-		Rv3823c	0.62	-0.8
4,290,438	+		Rv3823c	0.67	-0.1
4,290,550	-		Rv3823c	0.70	-1.0
4,290,711	-		Rv3823c	0.75	-1.4
4,290,751	-		Rv3823c	0.76	-1.3
4,291,001	-		Rv3823c	0.84	-1.2
4,291,172	-		Rv3823c	0.89	+1.9
4,291,172	-		Rv3823c	0.89	-1.1
4,291,415	+				-1.8
4,291,416	-				-1.2
4,291,416	-				-1.0
4,291,461	-				-0.3
4,291,476	+				-0.8
4,291,477	-				-0.5
4,291,640	+				-2.0
4,291,676	-				-0.4
4,291,821	+		Rv3824c	0.12	-1.2
4,291,950	-		Rv3824c	0.20	+0.1
4,292,211	+		Rv3824c	0.37	+0.3
4,292,260	-		Rv3824c	0.40	-0.1
4,292,523	-		Rv3824c	0.58	+0.4