Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1491c

Experiment: 7H9 with Ethambutol 0.75 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethambutol 0.75 ug/mL
1,680,342	+		Rv1490	0.78	-1.7
1,680,499	-				+0.1
1,680,499	-				-0.2
1,680,499	-				-0.2
1,680,670	-				+0.1
1,680,670	-				+0.4
1,680,718	+				-1.2
1,680,718	+				-0.0
1,680,718	+				-0.3
1,680,719	-				-0.3
1,680,719	-				-0.3
1,680,721	+				+0.5
1,680,722	-				+0.5
1,680,931	-				+1.3
1,680,948	+				+1.9
1,680,948	+				-0.1
1,680,948	+				-0.0
1,680,949	-				-0.2
1,680,964	+				-0.4
1,680,964	+				+0.5
1,680,964	+				-0.2
1,680,964	+				+0.4
1,680,989	-				-0.4
1,681,038	+				+0.0
1,681,039	-				-0.0
1,681,065	+				-0.5
1,681,066	-				-0.8
1,681,207	-				-0.2
1,681,242	+				-0.3
1,681,273	-				-0.8
1,681,323	-		Rv1491c	0.15	-0.8
1,681,323	-		Rv1491c	0.15	-0.5
1,681,464	+		Rv1491c	0.34	-0.7
1,681,464	+		Rv1491c	0.34	+0.0
1,681,465	-		Rv1491c	0.34	-0.3
1,681,465	-		Rv1491c	0.34	-0.2
1,681,658	+		Rv1491c	0.59	-0.6
1,681,658	+		Rv1491c	0.59	-0.3
1,681,659	-		Rv1491c	0.59	-0.5
1,681,739	-		Rv1491c	0.70	-0.9
1,681,739	-		Rv1491c	0.70	-0.2
1,681,838	+		Rv1491c	0.83	-0.8
1,681,996	+				-0.3
1,681,996	+				+3.3
1,681,996	+				-0.2
1,681,996	+				-0.1
1,681,996	+				+0.1
1,681,996	+				-0.5
1,681,997	-				-0.3
1,682,059	+				-0.2
1,682,060	-				-0.5
1,682,081	-				+0.7
1,682,131	-				+0.2
1,682,170	+				-0.1
1,682,189	-				-0.9
1,682,331	+				-0.5
1,682,580	+		Rv1492	0.23	+1.9
1,682,580	+		Rv1492	0.23	+0.2
1,682,580	+		Rv1492	0.23	-0.3
1,682,892	+		Rv1492	0.40	-0.3
1,682,893	-		Rv1492	0.40	+1.9