Experiment: 7H9 with Ethambutol 0.75 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1173 and Rv1174c are separated by 167 nucleotides Rv1174c and Rv1175c are separated by 200 nucleotides Rv1175c and Rv1176c overlap by 4 nucleotides Rv1176c and Rv1177 are separated by 212 nucleotides
Rv1173: Rv1173 - Probable F420 biosynthesis protein FbiC, at 1,302,931 to 1,305,501
Rv1173
Rv1174c: Rv1174c - Low molecular weight T-cell antigen TB8.4, at 1,305,669 to 1,306,001
Rv1174c
Rv1175c: Rv1175c - Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase), at 1,306,202 to 1,308,226
Rv1175c
Rv1176c: Rv1176c - Conserved hypothetical protein, at 1,308,223 to 1,308,792
Rv1176c
Rv1177: Rv1177 - Probable ferredoxin FdxC, at 1,309,005 to 1,309,331
Rv1177
Position (kb)
1306
1307
1308
1309 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1305.236 kb on + strand, within Rv1173 at 1305.236 kb on + strand, within Rv1173 at 1305.481 kb on + strand at 1305.670 kb on + strand at 1305.670 kb on + strand at 1305.671 kb on - strand at 1305.673 kb on + strand at 1305.673 kb on + strand at 1305.673 kb on + strand at 1305.715 kb on + strand, within Rv1174c at 1305.715 kb on + strand, within Rv1174c at 1305.716 kb on - strand, within Rv1174c at 1305.716 kb on - strand, within Rv1174c at 1305.800 kb on - strand, within Rv1174c at 1305.867 kb on + strand, within Rv1174c at 1305.868 kb on - strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.870 kb on + strand, within Rv1174c at 1305.871 kb on - strand, within Rv1174c at 1305.871 kb on - strand, within Rv1174c at 1305.871 kb on - strand, within Rv1174c at 1305.871 kb on - strand, within Rv1174c at 1305.896 kb on + strand, within Rv1174c at 1306.003 kb on + strand at 1306.004 kb on - strand at 1306.004 kb on - strand at 1306.004 kb on - strand at 1306.024 kb on - strand at 1306.024 kb on - strand at 1306.037 kb on + strand at 1306.037 kb on + strand at 1306.038 kb on - strand at 1306.144 kb on + strand at 1306.203 kb on + strand at 1306.205 kb on + strand at 1306.294 kb on + strand at 1306.295 kb on - strand at 1306.295 kb on - strand at 1306.359 kb on - strand at 1306.359 kb on - strand at 1306.416 kb on - strand, within Rv1175c at 1306.440 kb on + strand, within Rv1175c at 1306.554 kb on + strand, within Rv1175c at 1306.554 kb on + strand, within Rv1175c at 1306.771 kb on - strand, within Rv1175c at 1306.776 kb on - strand, within Rv1175c at 1306.997 kb on - strand, within Rv1175c at 1307.298 kb on - strand, within Rv1175c at 1307.560 kb on - strand, within Rv1175c at 1307.755 kb on - strand, within Rv1175c at 1307.892 kb on + strand, within Rv1175c at 1308.311 kb on + strand, within Rv1176c at 1308.311 kb on + strand, within Rv1176c at 1308.312 kb on - strand, within Rv1176c at 1308.426 kb on + strand, within Rv1176c at 1308.588 kb on - strand, within Rv1176c at 1308.589 kb on + strand, within Rv1176c at 1308.589 kb on + strand, within Rv1176c at 1308.589 kb on + strand, within Rv1176c at 1308.671 kb on + strand, within Rv1176c at 1308.672 kb on - strand, within Rv1176c at 1308.738 kb on - strand at 1308.831 kb on + strand at 1308.840 kb on - strand at 1308.840 kb on - strand at 1308.840 kb on - strand at 1308.850 kb on + strand at 1308.896 kb on - strand at 1308.898 kb on + strand at 1308.970 kb on + strand at 1308.970 kb on + strand at 1308.976 kb on + strand at 1308.976 kb on + strand at 1308.976 kb on + strand at 1308.976 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL remove 1,305,236 + Rv1173 0.90 -0.3 1,305,236 + Rv1173 0.90 +0.2 1,305,481 + +1.0 1,305,670 + -0.1 1,305,670 + +1.9 1,305,671 - -0.2 1,305,673 + -0.1 1,305,673 + +0.8 1,305,673 + -0.1 1,305,715 + Rv1174c 0.14 -1.4 1,305,715 + Rv1174c 0.14 +1.5 1,305,716 - Rv1174c 0.14 -0.7 1,305,716 - Rv1174c 0.14 -0.2 1,305,800 - Rv1174c 0.39 -0.4 1,305,867 + Rv1174c 0.59 -0.1 1,305,868 - Rv1174c 0.60 -2.0 1,305,870 + Rv1174c 0.60 +0.7 1,305,870 + Rv1174c 0.60 -0.3 1,305,870 + Rv1174c 0.60 -0.1 1,305,870 + Rv1174c 0.60 -0.4 1,305,870 + Rv1174c 0.60 -0.4 1,305,870 + Rv1174c 0.60 +0.1 1,305,871 - Rv1174c 0.61 -1.3 1,305,871 - Rv1174c 0.61 -0.3 1,305,871 - Rv1174c 0.61 -1.2 1,305,871 - Rv1174c 0.61 -2.0 1,305,896 + Rv1174c 0.68 +1.2 1,306,003 + -0.3 1,306,004 - -0.2 1,306,004 - -0.1 1,306,004 - +1.3 1,306,024 - +0.9 1,306,024 - -0.3 1,306,037 + +0.0 1,306,037 + -0.5 1,306,038 - -0.5 1,306,144 + -0.4 1,306,203 + -0.5 1,306,205 + +0.4 1,306,294 + +0.4 1,306,295 - -0.3 1,306,295 - -1.5 1,306,359 - +1.2 1,306,359 - -0.4 1,306,416 - Rv1175c 0.11 -0.2 1,306,440 + Rv1175c 0.12 +0.0 1,306,554 + Rv1175c 0.17 -0.2 1,306,554 + Rv1175c 0.17 -0.3 1,306,771 - Rv1175c 0.28 -0.2 1,306,776 - Rv1175c 0.28 +0.7 1,306,997 - Rv1175c 0.39 -0.1 1,307,298 - Rv1175c 0.54 +0.8 1,307,560 - Rv1175c 0.67 +0.3 1,307,755 - Rv1175c 0.77 -0.1 1,307,892 + Rv1175c 0.83 -0.3 1,308,311 + Rv1176c 0.15 -2.6 1,308,311 + Rv1176c 0.15 +0.3 1,308,312 - Rv1176c 0.16 -2.1 1,308,426 + Rv1176c 0.36 -0.2 1,308,588 - Rv1176c 0.64 +1.9 1,308,589 + Rv1176c 0.64 +2.3 1,308,589 + Rv1176c 0.64 +0.5 1,308,589 + Rv1176c 0.64 -0.6 1,308,671 + Rv1176c 0.79 +0.1 1,308,672 - Rv1176c 0.79 +0.9 1,308,738 - +0.3 1,308,831 + -0.7 1,308,840 - -0.4 1,308,840 - -0.7 1,308,840 - +0.6 1,308,850 + -0.5 1,308,896 - -0.2 1,308,898 + -0.5 1,308,970 + -0.3 1,308,970 + -0.1 1,308,976 + -0.3 1,308,976 + -0.1 1,308,976 + +1.3 1,308,976 + -0.2
Or see this region's nucleotide sequence