Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1104

Experiment: 7H9 with Ethambutol 0.75 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethambutol 0.75 ug/mL
1,230,422	-		Rv1101c	0.89	-0.0
1,230,457	+				+1.9
1,230,458	-				-0.4
1,230,458	-				+0.7
1,230,458	-				-0.1
1,230,472	+				-0.8
1,230,473	-				+1.9
1,230,473	-				-1.4
1,230,610	+				+0.0
1,230,611	-				-0.3
1,230,611	-				+0.3
1,230,611	-				-1.7
1,230,655	+				+1.0
1,230,656	-				+0.3
1,230,661	+				+0.0
1,230,661	+				+0.2
1,230,662	-				-3.6
1,230,662	-				+2.1
1,230,662	-				-0.8
1,230,662	-				-0.4
1,230,709	-		Rv1102c	0.16	-0.7
1,230,903	+		Rv1102c	0.78	-0.1
1,230,904	-		Rv1102c	0.78	+0.2
1,230,963	-				-0.2
1,230,963	-				+0.5
1,230,963	-				-0.3
1,230,963	-				+0.2
1,231,016	-		Rv1103c	0.14	-0.6
1,231,231	-		Rv1103c	0.81	+0.1
1,231,283	+				-0.0
1,231,287	+				+0.4
1,231,287	+				-0.2
1,231,287	+				-0.9
1,231,288	-				-1.1
1,231,288	-				+3.9
1,231,300	+				-0.6
1,231,301	-				-0.7
1,231,301	-				-0.8
1,231,301	-				+0.3
1,231,301	-				-0.5
1,231,301	-				+1.2
1,231,334	+				-0.0
1,231,392	-		Rv1104	0.13	+0.1
1,231,407	+		Rv1104	0.15	+0.8
1,231,408	-		Rv1104	0.16	-1.8
1,231,631	+		Rv1104	0.48	-0.2
1,231,631	+		Rv1104	0.48	+0.5
1,231,632	-		Rv1104	0.48	+1.0
1,231,661	+		Rv1104	0.52	+0.0
1,231,662	-		Rv1104	0.52	-0.2
1,231,662	-		Rv1104	0.52	+0.1
1,231,716	-		Rv1104	0.60	+0.7
1,231,825	-		Rv1104	0.76	+1.1
1,231,978	+				-0.3
1,231,979	-				+0.1
1,232,415	+		Rv1105	0.20	-0.0
1,232,488	+		Rv1105	0.34	+0.7
1,232,488	+		Rv1105	0.34	-1.0
1,232,488	+		Rv1105	0.34	-0.1
1,232,489	-		Rv1105	0.34	-0.0
1,232,566	+		Rv1105	0.49	+0.2
1,232,726	-		Rv1105	0.80	-0.2
1,232,836	-				+0.4
1,232,914	+				-0.9
1,232,914	+				+0.1
1,232,914	+				-0.3
1,232,914	+				-0.2
1,232,915	-				+0.3
1,232,915	-				-0.8
1,232,915	-				+0.7
1,232,915	-				+0.9
1,232,917	+				+0.3
1,232,918	-				-1.7
1,232,965	+		Rv1106c	0.11	-0.2
1,232,965	+		Rv1106c	0.11	-0.7
1,232,966	-		Rv1106c	0.11	-0.4