Experiment: 7H9 with Ethambutol 0.75 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3687c and Rv3688c are separated by 201 nucleotides Rv3688c and Rv3689 overlap by 1 nucleotides Rv3689 and Rv3690 are separated by 26 nucleotides Rv3690 and Rv3691 are separated by 125 nucleotides
Rv3687c: Rv3687c - Anti-anti-sigma factor RsfB (anti-sigma factor antagonist) (regulator of sigma F B), at 4,129,323 to 4,129,691
Rv3687c
Rv3688c: Rv3688c - Conserved protein, at 4,129,893 to 4,130,357
Rv3688c
Rv3689: Rv3689 - Probable conserved transmembrane protein, at 4,130,357 to 4,131,712
Rv3689
Rv3690: Rv3690 - Probable conserved membrane protein, at 4,131,739 to 4,132,392
Rv3690
Rv3691: Rv3691 - Conserved protein, at 4,132,518 to 4,133,519
Rv3691
Position (kb) 4130
4131
4132 Strain fitness (log2 ratio) -1
0
1
2 at 4129.649 kb on + strand, within Rv3687c at 4129.846 kb on - strand at 4129.871 kb on + strand at 4129.872 kb on - strand at 4129.873 kb on + strand at 4129.873 kb on + strand at 4129.873 kb on + strand at 4129.873 kb on + strand at 4129.873 kb on + strand at 4129.874 kb on - strand at 4129.874 kb on - strand at 4129.894 kb on + strand at 4129.895 kb on - strand at 4129.895 kb on - strand at 4129.896 kb on + strand at 4130.083 kb on + strand, within Rv3688c at 4130.083 kb on + strand, within Rv3688c at 4130.083 kb on + strand, within Rv3688c at 4130.149 kb on + strand, within Rv3688c at 4130.149 kb on + strand, within Rv3688c at 4130.150 kb on - strand, within Rv3688c at 4130.277 kb on + strand, within Rv3688c at 4130.278 kb on - strand, within Rv3688c at 4130.345 kb on + strand at 4130.405 kb on + strand at 4130.405 kb on + strand at 4130.405 kb on + strand at 4130.406 kb on - strand at 4130.528 kb on + strand, within Rv3689 at 4130.529 kb on - strand, within Rv3689 at 4130.561 kb on - strand, within Rv3689 at 4130.561 kb on - strand, within Rv3689 at 4130.588 kb on + strand, within Rv3689 at 4130.589 kb on - strand, within Rv3689 at 4130.606 kb on + strand, within Rv3689 at 4130.606 kb on + strand, within Rv3689 at 4130.606 kb on + strand, within Rv3689 at 4130.607 kb on - strand, within Rv3689 at 4130.625 kb on - strand, within Rv3689 at 4130.739 kb on + strand, within Rv3689 at 4130.739 kb on + strand, within Rv3689 at 4130.770 kb on + strand, within Rv3689 at 4130.770 kb on + strand, within Rv3689 at 4130.792 kb on + strand, within Rv3689 at 4130.792 kb on + strand, within Rv3689 at 4130.874 kb on + strand, within Rv3689 at 4130.874 kb on + strand, within Rv3689 at 4130.875 kb on - strand, within Rv3689 at 4131.169 kb on - strand, within Rv3689 at 4131.263 kb on + strand, within Rv3689 at 4131.264 kb on - strand, within Rv3689 at 4131.264 kb on - strand, within Rv3689 at 4131.264 kb on - strand, within Rv3689 at 4131.408 kb on + strand, within Rv3689 at 4131.409 kb on - strand, within Rv3689 at 4131.409 kb on - strand, within Rv3689 at 4131.508 kb on + strand, within Rv3689 at 4131.582 kb on + strand at 4131.584 kb on + strand at 4131.584 kb on + strand at 4131.585 kb on - strand at 4131.585 kb on - strand at 4131.639 kb on + strand at 4131.690 kb on + strand at 4131.690 kb on + strand at 4131.691 kb on - strand at 4131.691 kb on - strand at 4131.710 kb on + strand at 4131.710 kb on + strand at 4131.720 kb on + strand at 4131.808 kb on + strand, within Rv3690 at 4132.000 kb on + strand, within Rv3690 at 4132.103 kb on + strand, within Rv3690 at 4132.489 kb on - strand at 4132.669 kb on - strand, within Rv3691 at 4132.673 kb on - strand, within Rv3691
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL remove 4,129,649 + Rv3687c 0.88 -1.2 4,129,846 - -0.6 4,129,871 + +0.3 4,129,872 - +0.9 4,129,873 + +0.2 4,129,873 + +0.9 4,129,873 + -0.1 4,129,873 + -0.9 4,129,873 + -0.4 4,129,874 - +1.9 4,129,874 - +0.2 4,129,894 + -0.1 4,129,895 - -0.4 4,129,895 - +0.2 4,129,896 + -0.0 4,130,083 + Rv3688c 0.41 -0.5 4,130,083 + Rv3688c 0.41 -0.2 4,130,083 + Rv3688c 0.41 -0.2 4,130,149 + Rv3688c 0.55 -0.5 4,130,149 + Rv3688c 0.55 -0.4 4,130,150 - Rv3688c 0.55 -0.2 4,130,277 + Rv3688c 0.83 -0.6 4,130,278 - Rv3688c 0.83 -1.2 4,130,345 + -0.5 4,130,405 + +1.1 4,130,405 + +0.2 4,130,405 + +0.0 4,130,406 - -0.3 4,130,528 + Rv3689 0.13 -0.4 4,130,529 - Rv3689 0.13 +0.9 4,130,561 - Rv3689 0.15 +0.1 4,130,561 - Rv3689 0.15 +0.6 4,130,588 + Rv3689 0.17 -0.2 4,130,589 - Rv3689 0.17 -0.4 4,130,606 + Rv3689 0.18 +0.3 4,130,606 + Rv3689 0.18 +0.8 4,130,606 + Rv3689 0.18 -0.3 4,130,607 - Rv3689 0.18 +0.3 4,130,625 - Rv3689 0.20 -1.3 4,130,739 + Rv3689 0.28 -0.2 4,130,739 + Rv3689 0.28 -0.4 4,130,770 + Rv3689 0.30 +0.2 4,130,770 + Rv3689 0.30 +0.1 4,130,792 + Rv3689 0.32 -0.2 4,130,792 + Rv3689 0.32 -0.2 4,130,874 + Rv3689 0.38 +0.3 4,130,874 + Rv3689 0.38 +0.0 4,130,875 - Rv3689 0.38 +0.4 4,131,169 - Rv3689 0.60 +0.1 4,131,263 + Rv3689 0.67 +1.3 4,131,264 - Rv3689 0.67 +0.6 4,131,264 - Rv3689 0.67 -0.4 4,131,264 - Rv3689 0.67 +0.0 4,131,408 + Rv3689 0.78 +0.0 4,131,409 - Rv3689 0.78 +0.7 4,131,409 - Rv3689 0.78 +0.0 4,131,508 + Rv3689 0.85 +0.4 4,131,582 + +0.2 4,131,584 + -0.1 4,131,584 + +0.1 4,131,585 - -0.3 4,131,585 - +0.0 4,131,639 + -0.6 4,131,690 + -0.4 4,131,690 + -0.0 4,131,691 - -0.2 4,131,691 - +0.0 4,131,710 + -0.2 4,131,710 + -1.4 4,131,720 + -0.0 4,131,808 + Rv3690 0.11 +0.4 4,132,000 + Rv3690 0.40 +0.1 4,132,103 + Rv3690 0.56 +0.0 4,132,489 - -0.2 4,132,669 - Rv3691 0.15 +0.4 4,132,673 - Rv3691 0.15 -0.6
Or see this region's nucleotide sequence