Experiment: 7H9 with Ethambutol 0.75 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3490 and Rv3491 are separated by 151 nucleotides Rv3491 and Rv3492c overlap by 4 nucleotides Rv3492c and Rv3493c overlap by 1 nucleotides Rv3493c and Rv3494c overlap by 1 nucleotides
Rv3490: Rv3490 - Alpha, alpha-trehalose-phosphate synthase [UDP-forming] OtsA (trehalose-6-phosphate synthase) (UDP-glucose-glucosephosphate glucosyltransferase) (trehalosephosphate-UDP glucosyltransferase) (trehalose-6-phosphate synthetase) (trehalose-phosphate synthase) (trehalose-phosphate synthetase) (transglucosylase) (trehalosephosphate-UDP glucosyl transferase), at 3,908,236 to 3,909,738
Rv3490
Rv3491: Rv3491 - Unknown protein, at 3,909,890 to 3,910,468
Rv3491
Rv3492c: Rv3492c - Conserved hypothetical Mce associated protein, at 3,910,465 to 3,910,947
Rv3492c
Rv3493c: Rv3493c - Conserved hypothetical Mce associated alanine and valine rich protein, at 3,910,947 to 3,911,675
Rv3493c
Rv3494c: Rv3494c - Mce-family protein Mce4F, at 3,911,675 to 3,913,369
Rv3494c
Position (kb)
3910
3911 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4 at 3909.737 kb on - strand at 3909.855 kb on + strand at 3910.084 kb on + strand, within Rv3491 at 3910.085 kb on - strand, within Rv3491 at 3910.097 kb on + strand, within Rv3491 at 3910.148 kb on - strand, within Rv3491 at 3910.213 kb on + strand, within Rv3491 at 3910.214 kb on - strand, within Rv3491 at 3910.214 kb on - strand, within Rv3491 at 3910.214 kb on - strand, within Rv3491 at 3910.295 kb on + strand, within Rv3491 at 3910.296 kb on - strand, within Rv3491 at 3910.819 kb on + strand, within Rv3492c at 3911.060 kb on + strand, within Rv3493c at 3911.179 kb on - strand, within Rv3493c at 3911.179 kb on - strand, within Rv3493c at 3911.287 kb on + strand, within Rv3493c at 3911.375 kb on + strand, within Rv3493c at 3911.615 kb on + strand at 3911.616 kb on - strand at 3911.616 kb on - strand at 3911.664 kb on - strand at 3911.677 kb on - strand at 3911.753 kb on - strand at 3911.799 kb on + strand at 3911.799 kb on + strand at 3911.799 kb on + strand at 3911.800 kb on - strand at 3911.800 kb on - strand at 3911.808 kb on + strand at 3911.808 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL remove 3,909,737 - +0.1 3,909,855 + -0.3 3,910,084 + Rv3491 0.34 +0.2 3,910,085 - Rv3491 0.34 -0.9 3,910,097 + Rv3491 0.36 -0.3 3,910,148 - Rv3491 0.45 -0.9 3,910,213 + Rv3491 0.56 -0.4 3,910,214 - Rv3491 0.56 +0.6 3,910,214 - Rv3491 0.56 -0.4 3,910,214 - Rv3491 0.56 -0.5 3,910,295 + Rv3491 0.70 -0.6 3,910,296 - Rv3491 0.70 +1.9 3,910,819 + Rv3492c 0.73 -0.5 3,911,060 + Rv3493c 0.16 +0.1 3,911,179 - Rv3493c 0.32 +0.4 3,911,179 - Rv3493c 0.32 -1.6 3,911,287 + Rv3493c 0.47 -0.5 3,911,375 + Rv3493c 0.59 -0.2 3,911,615 + -2.1 3,911,616 - -0.1 3,911,616 - +0.2 3,911,664 - +0.5 3,911,677 - +0.9 3,911,753 - +0.4 3,911,799 + +0.1 3,911,799 + +1.2 3,911,799 + -0.4 3,911,800 - -0.5 3,911,800 - -1.1 3,911,808 + +3.9 3,911,808 + -0.9
Or see this region's nucleotide sequence