Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3120

Experiment: 7H9 with Ethambutol 0.75 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethambutol 0.75 ug/mL
3,485,092	+				-0.3
3,485,112	+				+0.1
3,485,112	+				+0.4
3,485,116	+				+0.5
3,485,116	+				+0.5
3,485,116	+				+1.9
3,485,116	+				-0.3
3,485,117	-				-0.1
3,485,145	+				+0.4
3,485,146	-				+0.0
3,485,165	+				-1.2
3,485,303	+		Rv3119	0.39	-0.7
3,485,485	+		Rv3119	0.80	-0.5
3,485,486	-		Rv3119	0.80	-0.2
3,485,566	+				-0.4
3,485,675	+		Rv3120	0.17	-2.0
3,485,925	-		Rv3120	0.59	-1.8
3,485,937	-		Rv3120	0.61	-1.5
3,485,937	-		Rv3120	0.61	-0.1
3,485,993	+		Rv3120	0.70	-0.2
3,485,994	-		Rv3120	0.70	-0.2
3,486,189	+				-0.7
3,486,189	+				+0.4
3,486,613	-				+0.9
3,486,613	-				+0.4
3,486,663	+		Rv3121	0.13	+2.0
3,486,664	-		Rv3121	0.13	+0.6
3,486,664	-		Rv3121	0.13	-0.2
3,486,816	+		Rv3121	0.26	+0.4
3,486,816	+		Rv3121	0.26	-1.0
3,486,921	+		Rv3121	0.34	-1.7
3,486,921	+		Rv3121	0.34	+0.1
3,486,921	+		Rv3121	0.34	+0.2
3,486,921	+		Rv3121	0.34	-0.8
3,486,922	-		Rv3121	0.34	-0.2
3,486,922	-		Rv3121	0.34	+0.0
3,486,924	+		Rv3121	0.34	+1.3
3,486,924	+		Rv3121	0.34	+0.2
3,486,925	-		Rv3121	0.35	-0.6
3,486,960	+		Rv3121	0.37	+0.5
3,486,961	-		Rv3121	0.38	-0.4
3,487,089	+		Rv3121	0.48	+1.4
3,487,090	-		Rv3121	0.48	+0.6
3,487,125	+		Rv3121	0.51	+0.1
3,487,125	+		Rv3121	0.51	-0.7
3,487,125	+		Rv3121	0.51	-0.1
3,487,125	+		Rv3121	0.51	+0.7
3,487,125	+		Rv3121	0.51	+1.0
3,487,125	+		Rv3121	0.51	-0.7
3,487,126	-		Rv3121	0.51	-0.2
3,487,126	-		Rv3121	0.51	+0.9
3,487,126	-		Rv3121	0.51	+0.0
3,487,126	-		Rv3121	0.51	-1.4
3,487,126	-		Rv3121	0.51	-0.5
3,487,126	-		Rv3121	0.51	-1.4
3,487,129	+		Rv3121	0.52	-0.3
3,487,129	+		Rv3121	0.52	+2.0
3,487,129	+		Rv3121	0.52	+0.2
3,487,129	+		Rv3121	0.52	-0.4
3,487,130	-		Rv3121	0.52	-0.3
3,487,130	-		Rv3121	0.52	-0.3
3,487,130	-		Rv3121	0.52	-0.1
3,487,130	-		Rv3121	0.52	-0.4