Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2560

Experiment: 7H9 with Ethambutol 0.75 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Ethambutol 0.75 ug/mL
2,879,133	+		Rv2559c	0.41	+0.2
2,879,134	-		Rv2559c	0.41	+0.1
2,879,157	+		Rv2559c	0.43	+0.0
2,879,158	-		Rv2559c	0.43	-0.6
2,879,363	+		Rv2559c	0.58	-0.5
2,879,363	+		Rv2559c	0.58	+0.7
2,879,367	-		Rv2559c	0.59	-0.6
2,879,367	-		Rv2559c	0.59	-0.6
2,879,674	-		Rv2559c	0.81	+1.9
2,879,719	-		Rv2559c	0.84	-0.5
2,879,719	-		Rv2559c	0.84	+0.2
2,879,719	-		Rv2559c	0.84	+0.2
2,879,929	+				+0.6
2,879,929	+				-0.6
2,879,929	+				-0.4
2,879,930	-				+0.9
2,880,000	+				-0.3
2,880,001	-				-1.7
2,880,008	-				-0.0
2,880,054	+				+0.3
2,880,144	+				+0.2
2,880,145	-				-0.4
2,880,186	+		Rv2560	0.11	-0.5
2,880,207	+		Rv2560	0.13	-0.4
2,880,207	+		Rv2560	0.13	-0.1
2,880,207	+		Rv2560	0.13	+0.0
2,880,207	+		Rv2560	0.13	-0.4
2,880,208	-		Rv2560	0.14	+0.2
2,880,208	-		Rv2560	0.14	-0.4
2,880,223	-		Rv2560	0.15	-0.4
2,880,344	+		Rv2560	0.28	-0.4
2,880,390	+		Rv2560	0.32	-0.1
2,880,391	-		Rv2560	0.32	-2.2
2,880,458	+		Rv2560	0.39	-0.4
2,880,458	+		Rv2560	0.39	-0.9
2,880,458	+		Rv2560	0.39	-0.4
2,880,459	-		Rv2560	0.39	-0.1
2,880,461	+		Rv2560	0.39	-0.5
2,880,469	-		Rv2560	0.40	-0.8
2,880,532	+		Rv2560	0.47	+1.5
2,880,532	+		Rv2560	0.47	-0.8
2,880,559	+		Rv2560	0.49	-0.6
2,880,560	-		Rv2560	0.50	-0.0
2,880,576	+		Rv2560	0.51	-0.6
2,880,577	-		Rv2560	0.51	-0.0
2,880,650	+		Rv2560	0.59	-1.0
2,880,960	+				+0.0
2,880,961	-				+0.3
2,880,961	-				-0.4
2,880,961	-				+0.9
2,881,141	+				-0.1
2,881,171	-				-0.3
2,881,171	-				-0.3
2,881,186	+				-0.0
2,881,186	+				+0.8
2,881,186	+				-0.1
2,881,187	-				-0.1
2,881,187	-				-0.5
2,881,190	+				+0.0
2,881,191	-				-0.3
2,881,217	+				-0.3
2,881,217	+				-0.2
2,881,218	-				-2.8
2,881,218	-				-0.2
2,881,221	+				+0.2
2,881,308	+				-0.3
2,881,454	+		Rv2561	0.15	-1.9
2,881,463	+		Rv2561	0.18	-0.2
2,881,463	+		Rv2561	0.18	-0.1
2,881,463	+		Rv2561	0.18	-0.2
2,881,463	+		Rv2561	0.18	-1.5
2,881,463	+		Rv2561	0.18	+0.0
2,881,463	+		Rv2561	0.18	-0.5
2,881,463	+		Rv2561	0.18	-0.6
2,881,464	-		Rv2561	0.19	-1.3
2,881,621	+		Rv2561	0.72	-1.2
2,881,701	-				+0.7
2,881,855	-		Rv2562	0.25	-0.6
2,881,855	-		Rv2562	0.25	+0.3
2,881,855	-		Rv2562	0.25	+1.9
2,881,855	-		Rv2562	0.25	+0.0
2,881,858	+		Rv2562	0.26	+0.9
2,881,858	+		Rv2562	0.26	+1.6
2,881,859	-		Rv2562	0.26	-0.7
2,881,859	-		Rv2562	0.26	-0.4
2,881,859	-		Rv2562	0.26	+0.9
2,881,876	+		Rv2562	0.30	-0.5
2,881,909	+		Rv2562	0.39	-0.1
2,881,962	+		Rv2562	0.52	-0.2
2,881,962	+		Rv2562	0.52	-0.2
2,881,962	+		Rv2562	0.52	+0.5
2,881,963	-		Rv2562	0.53	+0.4
2,881,963	-		Rv2562	0.53	+0.1