Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1929c

Experiment: 7H9 with Ethambutol 0.75 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1927 and Rv1928c are separated by 3 nucleotidesRv1928c and Rv1929c are separated by 44 nucleotidesRv1929c and Rv1930c are separated by 11 nucleotidesRv1930c and Rv1931c are separated by 17 nucleotides Rv1927: Rv1927 - Conserved hypothetical protein, at 2,179,673 to 2,180,446 Rv1927 Rv1928c: Rv1928c - Probable short-chain type dehydrogenase/reductase, at 2,180,450 to 2,181,217 Rv1928c Rv1929c: Rv1929c - Conserved hypothetical protein, at 2,181,262 to 2,181,906 Rv1929c Rv1930c: Rv1930c - Conserved hypothetical protein, at 2,181,918 to 2,182,442 Rv1930c Rv1931c: Rv1931c - Probable transcriptional regulatory protein, at 2,182,460 to 2,183,239 Rv1931c Position (kb) 2181 2182Strain fitness (log2 ratio) -1 0 1 2 3at 2180.296 kb on + strand, within Rv1927at 2180.296 kb on + strand, within Rv1927at 2180.464 kb on - strandat 2180.497 kb on + strandat 2180.500 kb on - strandat 2180.524 kb on - strandat 2180.599 kb on - strand, within Rv1928cat 2180.608 kb on - strand, within Rv1928cat 2181.127 kb on - strand, within Rv1928cat 2181.127 kb on - strand, within Rv1928cat 2181.354 kb on - strand, within Rv1929cat 2181.685 kb on - strand, within Rv1929cat 2181.685 kb on - strand, within Rv1929cat 2181.685 kb on - strand, within Rv1929cat 2181.705 kb on + strand, within Rv1929cat 2181.828 kb on + strand, within Rv1929cat 2181.828 kb on + strand, within Rv1929cat 2181.829 kb on - strand, within Rv1929cat 2182.382 kb on - strand, within Rv1930cat 2182.418 kb on - strandat 2182.494 kb on - strandat 2182.838 kb on + strand, within Rv1931cat 2182.838 kb on + strand, within Rv1931c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Ethambutol 0.75 ug/mL
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2,180,296 + Rv1927 0.80 -0.2
2,180,296 + Rv1927 0.80 +0.2
2,180,464 - -0.6
2,180,497 + -0.4
2,180,500 - +1.7
2,180,524 - -0.8
2,180,599 - Rv1928c 0.19 -0.8
2,180,608 - Rv1928c 0.21 -0.5
2,181,127 - Rv1928c 0.88 +0.7
2,181,127 - Rv1928c 0.88 -0.3
2,181,354 - Rv1929c 0.14 +0.5
2,181,685 - Rv1929c 0.66 +0.3
2,181,685 - Rv1929c 0.66 +2.9
2,181,685 - Rv1929c 0.66 -0.9
2,181,705 + Rv1929c 0.69 -0.7
2,181,828 + Rv1929c 0.88 +0.7
2,181,828 + Rv1929c 0.88 -0.2
2,181,829 - Rv1929c 0.88 -0.3
2,182,382 - Rv1930c 0.88 -0.7
2,182,418 - -0.7
2,182,494 - +0.9
2,182,838 + Rv1931c 0.48 -0.1
2,182,838 + Rv1931c 0.48 -0.1

Or see this region's nucleotide sequence